2016 Collaborative Study on Aromatic Amines in Mainstream Cigarette Smoke
SMA Technical Report
From 2014 to 2017, the CORESTA Special Analytes Sub-Group (SPA) (now named Smoke Analytes Sub-Group, SMA) evaluated through a series of joint experiments and a Collaborative Study an analytical method for measurement of aromatic amines.
This report covers the Collaborative Study undertaken to evaluate the GC/MS(NCI) method for the determination of aromatic amines in ISO and HCI mainstream smoke of a range of products using HFBA as the derivatisation agent and Florisil SPE as a sample clean-up.
The generated data and corresponding statistical analysis indicated that the analytical method currently does not support development of a CORESTA Recommended Method (CRM). However, several aspects of the methodology were identified as key for further investigation, especially optimisation of SPE clean-up and derivatisation, and an amended method will be tested on reference products.
CRM 95 - Determination of Aromatic Amines in Mainstream Cigarette Smoke by Gas Chromatography Mass Spectrometry with Negative Chemical Ionisation (GC/MS(NCI)) (January 2021)
Report - 2019 Small Group Collaborative Study on Aromatic Amines in Mainstream Cigarette Smoke (May 2020)
Report - 2016 Joint Experiment on Aromatic Amines in Mainstream Cigarette Smoke by LC-MS/MS (November 2019)
Report - Determination of Aromatic Amines in Cigarette Mainstream Smoke. The CORESTA 2007 Joint Experiment (July 2010)