Reports current

2019 Collaborative Study for B[a]P and TSNA Compounds in Mainstream Cigar Smoke

SA Technical Report

June 2022 Ref. SMA-SA-198-1-CTR

In 2019, a collaborative study (CS) was launched in an effort to expand the scopes of CRM No. 75 and CRM No. 58, currently only valid for cigarettes, to include cigar smoke analysis for tobacco specific nitrosamines (TSNAs) and benzo[a]pyrene (B[a]P), respectively. Additionally, an experiment to determine the feasibility of simultaneous analysis for volatile organics (VO) (CRM No. 70/ISO 21330) was included.

The smoking related parameters were reviewed and statistical analysis was carried out following the ISO standard 5725 to generate repeatability (r) and reproducibility (R) for TSNAs.

Based on the results of this study, CRM No. 75 will be updated to include initial r&R values for TSNA analytes.  B[a]P participation was too low to warrant the addition of even preliminary r&R values to the CRM. The feasibility experiment with volatile organics (VO) indicates that this work has merit and should be considered for inclusion in SA SG plans as priority and timing allows.


Related documents

CRM 75 - Determination of Tobacco Specific Nitrosamines in Mainstream Smoke by LC-MS/MS (September 2022)

CRM 70 - Determination of Selected Volatile Organic Compounds in the Mainstream Smoke of Cigarettes - Gas Chromatography-Mass Spectrometry Method (September 2019)

CRM 58 - Determination of Benzo[a]pyrene in Cigarette Mainstream Smoke by Gas Chromatography-Mass Spectrometry (November 2019)

Report - Cigar Smoke Analysis - 14th Collaborative Study (April 2021)

Report - 2018 Collaborative Study of CORESTA Monitor 8 (CM8) and 9 (CM9) for the Determination of Test Piece Weight, TPM, Water, Nicotine, NFDPM, Carbon Monoxide and Puff Count Obtained under Mainstream ‘ISO’ and ‘Intense’ Smoking Regimes (February 2019)