2021 Nicotine Pouches Collaborative Study
TTPA Technical Report
Nicotine pouches, or white pouches, are oral tobacco products that contain tobacco derived nicotine, but not tobacco leaf. As at October 2020, there were no standardized methods available for the analysis of nicotine pouches even though there are regulatory reporting requirements.
A collaborative study was therefore carried out with the intent to update the scopes of the applicable CORESTA Recommended Methods (CRMs) to also include nicotine pouches and to provide repeatability (r) and reproducibility (R) results and z-scores to support laboratory accreditation.
The results of the study demonstrated that the CRMs for the determination of nicotine, pH, moisture (oven volatiles), tobacco-specific nitrosamines (TSNAs), water activity, metals, carbonyls, and benzo[a]pyrene (B[a]P) were suitable for the analysis of nicotine pouches and it was recommended that the eight CRMs be updated to include nicotine pouches.
CRM 93 - Determination of Selected Metals in Tobacco Products by ICP-MS (July 2020)
CRM 88 - Determination of Water Activity of Tobacco and Tobacco Products (January 2019)
CRM 86 - Determination of Select Carbonyls in Tobacco and Tobacco Products by UHPLC-MS/MS (January 2018)
CRM 82 - Determination of Benzo[a]pyrene in Tobacco Products by GC-MS (March 2018)
CRM 76 - Determination of Moisture Content (Oven Volatiles) of Tobacco and Tobacco Products (July 2017)
CRM 72 - Determination of Tobacco Specific Nitrosamines in Tobacco and Tobacco Products by LC-MS/MS (July 2017)
CRM 69 - Determination of pH in Tobacco and Tobacco Products (July 2017)
CRM 62 - Determination of Nicotine in Tobacco and Tobacco Products by Gas Chromatographic Analysis (December 2021)