In 2021, a project was launched with the objective to establish a CRM for analysis for oxides of nitrogen (NOx) in mainstream cigarette smoke.

The study design included reference and monitor samples across a range of nominal ISO 3308 tar levels and use of an intense and non-intense regime in order to evaluate methodology across a broad analyte and matrix level. Laboratories reported method details, basic smoking measures and NOx, and optionally, NO yields.

Based on the results of this study, a CORESTA Recommended Method will be developed for the determination of NOx in cigarette smoke by chemiluminescence.