The fauna of Noctuidae and subfamily Melicleptrinae in Yugoslavia, especially in Macedonia is considerably rich in its species content. Up to now, 19 species are stated to belong to this group of moths. The most dangerous species Macedonia is Helicoverpa armigera (Hbn). All stages of development of H. armigera have their natural enemies which control and reduce the population of this dangerous species. The most effective among them are the insects _ parasites and the viruses. The insects _ parasites are, however, on the first place because some of the species appear in connection and succession, which is not the case with the other groups of natural enemies. Out of the field and laboratory investigations, it could be stated that the quality content of parasites in Macedonia is considerably rich. The most important of them are the parasites that belong to the order of Hymenoptera : Microbracon brevicorins Wesm., Apanteles sp. (Kasak), Hypozoter didimator (larvae parasites) and Telenomus sp. (egg parasites). Total reduction of the population of H. armigera is very high : from 66.30% in 1974 to 93% in 1979.