Comparative assessment of selected compounds yields in heated tobacco products
A diverse range of heated tobacco products (HTPs) has been introduced in a growing number of markets by different manufacturers. They generally differentiate from cigarettes by the absence of combustion and a significant reduction in the levels of harmful and potentially harmful constituents (HPHCs) emitted. The purpose of this study was to propose a standardized method to generate HTP aerosols and to report the obtained HPHC yields in order to perform a comparative assessment of the different products. The yields of selected compounds, such as nicotine, CO, nitrogen oxides, tobacco-specific nitrosamines (TSNAs), and volatile organic compounds were measured in commercially available products, covering different types of HTPs (electrically heated products, hybrid products, tobacco vaporisers), using standardized conditions. The yields of TSNAs and nicotine were the most variable, while the yields of other HPHCs, linked to tobacco degradation at high temperatures (e.g. CO, benzene, or benzo[a]pyrene), were very low for all products in comparison with yields found in cigarette mainstream smoke. The robustness of the products toward slight changes in the aerosol generating regime was also examined on the basis of HPHC yields in aerosols. The use of a reporting per volume basis allowed comparison of results obtained with different puffing regimes. It was found that not all HTPs show the same behavior toward changes in the puffing regime.