Topping at onset of flowering is a standard practice in the production of flue-cured tobacco. Subsequently, axillary buds begin to grow into suckers. Suckering is the removal operation of the suckers. It is well known that topping and suckering have a pronounced effect on the cured leaf. Yield and return are increased and alkaloids and reducing sugar levels as well as other chemical constituents are altered. Normally, the yield increase is greater when topping and suckering have been done, when compared to the topped and not suckered plants; however, high yielding plants can produce lower quality tobacco. The potential of a flue-cured tobacco to produce high yields, desired quality and grade composition can be markedly influenced by the time of control of axillary bud growth whether the tobacco is topped or not. The goal of this study was to analyze the relation between nitrogen levels and sucker control at different stages of growth, with the purpose to produce qualities which respond to world requirements.