The determination and comparison of ammonia content in tobacco products by ion chromatography and continuous flow analysis
The FDA Center for Tobacco Products (CTP) has identified ammonia as a harmful or potentially harmful constituent (HPHC) in tobacco and tobacco products. However, there is currently not a single, generally accepted method for the determination of ammonia in tobacco products. For this study, three methods were used - ion chromatography by CORESTA Recommended Method (No. 73), a modified version of CORESTA Recommended Method (No. 73) using a C-16 column, and Continuous Flow Analysis (CFA). All these methods are routinely used for the quantification of ammonia in tobacco and tobacco products. We will present the ammonia concentration determined in 3R4F blend, CM7 blend and CRP3 smokeless tobacco by each method. The results for each method will be compared along with the advantages and disadvantages of each analytical technique.