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TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 22

The effect of design parameters on yields of 33 harmful and potentially harmful constituents (HPHCs) in mainstream smoke of large cigars

United States Food and Drug Administration, Silver Spring, MD, USA

The effect of design parameters on a large cigar’s mainstream smoke yields of harmful and potentially harmful constituents (HPHCs) is relatively unstudied. Furthermore, available chemical analysis research on large cigars has focused on tar and a limited number of HPHCs (e.g., nicotine, carbon monoxide, benzo[a]pyrene and select carbonyls) and many recognized smoke HPHCs have been largely overlooked. To bridge this gap, the smoke yields of 33 HPHCs were measured in 10 large cigar brands using the Canadian Intense regimen (55 mL puff volume, 30 sec puff frequency, 2 sec puff duration, 100% vent block, if applicable) to produce mainstream smoke. HPHC yields were plotted against the cigars’ design parameters (total cigar weight, tobacco filler weight, length, circumference, pressure drop, and estimated density and volume) and analyzed using simple linear regression. The influence of each design parameter on individual HPHC yields was evaluated using the plots’ slopes and correlation coefficients (R2), and P values were used to ensure that the slopes were significant. Cigar length, product mass, tobacco mass, and estimated volume were positively correlated to smoke yields of several classes of HPHCs including tobacco alkaloids (anabasine and nornicotine), carbonyls (acetone, methyl ethyl ketone, and propionaldehyde), and volatile and semi-volatile organic compounds (ethyl benzene, styrene, benzofuran, and furan). In the present study, in general, tobacco rod density and cigar circumference did not consistently correlate to any class of HPHCs and pressure drop did not correlate with any individual HPHC yields.