Tobacco transplanted 5 April tended to have a higher incidence of black shank disease than tobacco transplanted 5 May in 1983. The combination of metalaxyl and fenamiphos reduced black shank disease in both plantings over the untreated control. Yields were higher in the 5 May planting than in the 5 April planting, except for one treatment in which there were no differences. In 1984, black shank was reduced by all treatments for the 6 April and 15 May plantings, and by all treatments containing metalaxyl for the 26 April planting. Generally, black shank was reduced for a particular treatment as the transplanting date was delayed. For all three transplanting dates in 1984, root-knot indices were reduced by treatments having fenamiphos. There was a general trend for a reduction in root-knot damage as the transplanting date was delayed. Generally, yields tended to decline as the transplanting date was delayed. Value/ha correlated with yields. The grade index tended to be higher in the 26 April planting compared to the 6 April and 15 May plantings. Nitrogen content of leaves was not different for any treatment. However, total alkaloids and percent reducing sugars differed in some of the chemical treatments.