In the frame of a research on seedling production, the influence of physiologically active solutions on the germination of tobacco seed was investigated. The experiments were conducted using Baragan 132, a broad-leaf cultivar specific to our country. The following physiologically active substances were used:- procaine hydrochlorate at concentrations of: 0.05%; 0.1%; 0.2%; nicotinic acid at concentrations of: 0.05%; 0.1%; 0.3%; indole-acetic acid (AIA) at concentrations of: 0.01%; 0.05%; naphtyl-acetic acid (ANA) at concentrations of: 0.01%; 0.05%; thiourea at concentrations of: 0.1%; 0.2%; 0.3%. The check product was water. The tobacco seeds were treated for 24 hours with these products, then left to dry and placed in Petri dishes for germination. The germinating energy and the germination of the tobacco seeds were determined according to standards, and expressed in absolute values and relative values compared with the check. Results: the use of lower concentrations encouraged the germination and germinating energy of the seeds, while the higher concentrations had an inhibitive effect upon germination. Compared with the check: procaine hydrochlorate at concentrations of 0.05%; 0.1% and 0.2% improved germinating energy by 7 - 14% and germination by 9 - 11%; nicotinic acid at concentrations of 0.05% and 0.1% improved germinating energy by 8 - 10%, but germination had values close to the check; the concentration of 0.3% led to a decrease of germinating energy by 4% and of germination by 5%; AIA and ANA, at concentrations of 0.01% - 0.05%, improved germinating energy by 5 - 10% and germination by 8 - 13%; thiourea at concentrations of 0.1 - 0.2% improved germination by 4 - 9%; The use of procaine hydrochlorate also reduced the time of emergence of radicels, to approx. 24 hours after treatment of the seed. The seedlings obtained from treated seed were healthy, vigorous and uniformly developed and these characteristics led to significant yield increases.