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TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 51

The modular puff machine (MPM): a new approach to puffing

Juul Labs, Inc., Washington, DC, USA

The Juul Labs, Inc designed and developed Modular Puff Machine (MPM) is a contemporary alternative to traditional puff (i.e. aerosol collection) machines from manufacturers such as Borgwaldt and Cerulean. Traditional puff machines use a piston to draw a specified volume of air in a given amount of time through an e-cigarette/heated tobacco device and in-line sample collection equipment (e.g. filter pads and impingers). The MPM uses a mass flow controller connected to a vacuum source and employs flow control to establish puffing volumes and profiles. The MPM has several advantages over conventional puff machines, including its ability to draw large puff volumes, modularity in that the MPMs can be operated as independent single units or cooperatively in groups as large as twelve, user interface customization that can streamline and simplify workflows, over-the-air firmware updates for fleetwide bug fixes and feature updates, the ability to stream device and puff machine data directly to the cloud for subsequent analysis of individual puff profiles or machine performance, device charging between puffs as well as between tests, and user-defined "flushing puffs" that can move static aerosols in tubing onto filter pads or for subsequent analysis. This work focuses on comparing collected aerosols on both an MPM and traditional puff machines to investigate the impact of adding variable resistances such as filter pads and impingers into the flow path. Delivery of major e-liquid constituents (in mg/puff) was found to be comparable for glycerol (Borgwaldt: 3.7±0.2; MPM: 3.8±0.3), propylene glycol (Borgwaldt: 4.6±0.3; MPM: 4.8±0.2) and nicotine (Borgwaldt: 0.30±0.04; MPM: 0.28 ±0.02). Select carbonyls (formaldehyde, acetaldehyde, and acrolein) were also measured on both types of puff machines and found to be equivalent.