This paper describes a system for cigarette testing measuring fresh TPM (total particulate material) mass, median particle diameter, and particle number concentration, with any desired flow profile. This allows measurements at conditions representative of human smoking or for regulatory pre-defined machine smoking profiles. The data are collected at 10 Hz time resolution with cumulative number and TPM mass measurement in real time on a puff by puff basis. The system is designed to be used with real-time aerosol instruments such as DMS-type fast electrical mobility spectrometers to provide continuous measurement of the aerosol inhaled from the cigarette during smoking. The flow through the cigarette is metered with an orifice-?p type flow sensor and controlled to follow a specified profile at 12.5 Hz. To follow highly dynamic puff profiles a feed-forward type controller is used. The complete smoking of a cigarette with a different profile for each puff can be reproduced. The flow drawn through the cigarette is diluted with filtered air close to the filter holder to halt agglomeration processes. The system operates with a constant total diluted flow to minimise errors in the measurement of total mass emissions from the cigarette. A dilution ratio signal is provided to allow calculation of the undiluted concentrations if desired. The system has been tested with standard machine profiles and those measured from human smokers. Control of cigarette flows down to approximately 1 cc/s is possible, with a dynamic range of at least 30:1. The typical error in the integrated volume of a puff is around 1%. Puff by puff were measurements carried out on a series of 1- and 4-mg yielding products using a 35 ml puff of 2 s duration every 60 s, using an ISO puff profile, and normalised to 7 puffs. These data were compared on a puff by puff basis with gravimetric measurements. Count median diameters (CMD) were measured puff by puff and ranged from 163 - 247 nm, depending on the puff number and yield of each puff. Individual puffs were measured from 0.18 to 1.05 mg TPM and correlated well with the equivalent gravimetric data (r2 = 0.88).