Taking the flue-cured tobacco of different appearance quality from the production base of full flavor style tobacco leaf of Shanghai Tobacco (Group) Corporation in Xiangcheng, Henan Province as samples, the influence of leaf appearance on smoking quality was investigated, and the effects of two important aroma precursors, plastid pigment and polyphenol, on smoking quality indexes (including aroma quality, aroma quantity, offensive odor and aftertaste) were studied with canonical correlation analysis. The results showed that: 1) Light orange and orange upper leaves and orange middle leaves presented better smoking quality; in the range of “ripe” specified by national standard, the upper leaves near lower limit of ripe and middle leaves of average ripe better fitted the requirements of Shanghai Group. The aroma quality of upper leaves improved with the increase of leaf oil, while that of middle leaves with less oil was better. 2) The canonical correlation analysis indicated that plastid pigment and polyphenol were closely related with the smoking quality, especially aroma quality, of full flavor style tobacco. Lutein, chlorophyll, neochlorogenic acid and coffee quinic acid were negatively correlated with aroma quantity, while β-carotene, carotenoid, chlorogenic acid and rutin were obviously positively correlated with aroma quality.