The objective of this study was to screen strains able to degrade quinclorac efficiently. The strains were isolated from the perennial administration quinclorac paddy fields. The strain MC-10, which can degrade quinclorac efficiently, was screened by enrichment and selective medium. The strain was identified by morphological, physio-biochemical characteristics and 16S rRNA gene sequence analysis. MC-10 was identified as Arthrobacter sp. Under the optimal growth conditions with inoculum concentration of 5%, at 28 °C, pH 7 for 7 days, MC-10 had high biological activity and can degrade more than 90% of quinclorac. Degradation conditions for MC-10 are best at pH 7 and 30 °C. MC-10 can effectively degrade quinclorac when quinclorac initial concentration is within the range 1-100 ppm. And the strain MC-10 has a good ability to survive in the soil. More than 70% quinclorac in the soil can be degraded efficiently after four days of cultivation. These results indicated that Arthrobacter sp. MC-10 could be a promising microorganism in dealing with quinclorac pollution. Degradation of quinclorac can reduce the influence of pesticide residues in soil to the next crops, which will have a positive impact on reducing environmental and soil pollution and have positive economic and social benefits.