1. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 19

    Human mouth-level transfer rate of menthol, 1.8-cineole and nicotine from Swedish pouched snus

    TROUDE V.(1); GADOIS-POMMEREUL S.(1); CLARKE A.(2); SIMMS L.(2)
    (1) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France; (2) Imperial Tobacco Limited, Bristol, U.K.
    To facilitate the development of a transfer model which can be used to estimate human exposure to flavour and tobacco constituents, a human in vivo study involving 198 Swedish active snus users was conducted. All subjects agreed to participate in the...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, STPOST 03

    Analytical method to model human mouth-level transfer of ingredients from Swedish pouched snus

    GRAPTON S. (1); GADOIS-POMMEREUL S.(1); TROUDE V.(1); BLANCHET M. (1); CLARKE A.(2); SIMMS L.(2)
    (1) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France; (2) Imperial Tobacco Limited, Bristol, U.K.
    In parallel with the human study[1] a laboratory in vitro assay was conducted with three media: artificial saliva, water and 1% ß-cyclodextrin in water, using two snus products that were indistinguishable apart from the flavour application rate. To...
  3. CORESTA Congress, Paris, 2006, SSPOST 10

    Heterocyclic aromatic amines in cigarettes smoke: chemical and biological assessments

    TEILLET B.; COUILLARD V.; BLIN N.; SEVESTRE O.; ACHARD S.; TROUDE V.
    Altadis Research Centre, Fleury-les-Aubrais, France
    To explicit the contribution of Heterocyclic Aromatic Amines (HAA) on the toxicity of mainstream cigarette smoke, both developments of chemical and biological analyses are required. The successful of HAA (IQ, MeIQ, Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2,...