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28 results

  1. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 06

    Analysis of (S)- and (R)-nicotine in commercial nicotine samples and e-liquids and (R)-nicotine pharmacology

    DULL G.M.(1); MOLDOVEANU S.C.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco, Winston-Salem, NC, USA
    Nicotine has been studied extensively because of its presence in tobacco products. Because of its chirality, nicotine can exist in two enantiomeric forms; however, the tobacco plant produces predominantly (S)-nicotine with only a trace of...
  2. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 73

    A versatile method for the analysis of tsnas in tobacco products and cigarette smoke by LC-MS-MS

    ZHU J.(1); QIAN N.(1); JONES S.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    A versatile method for the analysis of TSNAs has been applied to different tobacco sample matrices such as tobacco filler, smokeless and raw tobacco materials, as well as cigarette smoke. The method used an HPLC separation on a Phenomenex Gemini C18...
  3. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 29

    Analysis of free amino acids in tobacco, and validation on the Agilent 6490 LC-MS-MS system

    ZHU J.(1); QIAN N.(1); WILKINS J.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The present study describes a number of improvements and changes performed on a LC-MS-MS method for the analysis of amino acids in tobacco which was initially developed using an Agilent 1200 HPLC and a Sciex API 5000 MS-MS, and has been previously...
  4. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 40

    Nicotine activity in tobacco

    ST.CHARLES F.K.(1); MOLDOVEANU S.C.(2)
    (1) St. Charles Consultancy, Lewisville, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The vapor pressure of pure nicotine has been reported in the literature. However, to the best of our knowledge, measurements of the vapor pressure of nicotine from tobacco have not been reported. Nicotine migration from tobacco to cigarette filters...
  5. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 38

    The migration during storage, transfer to smoke, and filtration efficiency of nicotine, glycerin, and propylene glycol in cigarettes.

    ST. CHARLES F.K.(1); MOLDOVEANU S.C.(2); MILLS H.D.(2); ANDRESEN N.P.(2)
    (1) St.Charles Consultancy, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Co., Winston Salem, NC, USA
    This study evaluated the migration during storage, transfer to smoke and filtration of nicotine, glycerin and propylene glycol (PG) for cigarettes with cellulose acetate/triacetin filters. Filtration efficiency (FE) and smoke yields were studied for...