Search Results

24 results

  1. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 73

    A versatile method for the analysis of tsnas in tobacco products and cigarette smoke by LC-MS-MS

    ZHU J.(1); QIAN N.(1); JONES S.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    A versatile method for the analysis of TSNAs has been applied to different tobacco sample matrices such as tobacco filler, smokeless and raw tobacco materials, as well as cigarette smoke. The method used an HPLC separation on a Phenomenex Gemini C18 ...
  2. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 29

    Analysis of free amino acids in tobacco, and validation on the Agilent 6490 LC-MS-MS system

    ZHU J.(1); QIAN N.(1); WILKINS J.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The present study describes a number of improvements and changes performed on a LC-MS-MS method for the analysis of amino acids in tobacco which was initially developed using an Agilent 1200 HPLC and a Sciex API 5000 MS-MS, and has been previously ...
  3. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 40

    Nicotine activity in tobacco

    ST.CHARLES F.K.(1); MOLDOVEANU S.C.(2)
    (1) St. Charles Consultancy, Lewisville, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The vapor pressure of pure nicotine has been reported in the literature. However, to the best of our knowledge, measurements of the vapor pressure of nicotine from tobacco have not been reported. Nicotine migration from tobacco to cigarette filters during ...
  4. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 38

    The migration during storage, transfer to smoke, and filtration efficiency of nicotine, glycerin, and propylene glycol in cigarettes.

    ST. CHARLES F.K.(1); MOLDOVEANU S.C.(2); MILLS H.D.(2); ANDRESEN N.P.(2)
    (1) St.Charles Consultancy, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Co., Winston Salem, NC, USA
    This study evaluated the migration during storage, transfer to smoke and filtration of nicotine, glycerin and propylene glycol (PG) for cigarettes with cellulose acetate/triacetin filters. Filtration efficiency (FE) and smoke yields were studied for two ...
  5. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 06

    Quantitative determination of Amadori compounds in tobacco using ion exchange liquid chromatography tandem mass spectrometry (LC-MS/MS)

    GERARDI A.; BYRD C.H.; MOLDOVEANU S.C.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Amadori compounds are formed during non-enzymatic browning of reducing sugars and amino acids and are important in the aroma of agricultural and food products. These compounds form naturally in tobacco and are of importance to the flavor profile of smoke. ...
  6. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 64

    Sensitive method for the determination of acrylamide in tobacco filler and alternative tobacco products by UPLC-MS/MS

    CHENG T.; QIAN N.; DENNIS M.; MOLDOVEANU S.C.; GERARDI A.R. (presented by CHOUCHANE S.)
    Lancaster Laboratories Inc., Lancaster, PA, USA; (2)R. J. Reynolds Tobacco Co., WinstonSalem, NC, USA
    A sensitive method for the analysis of acrylamide in tobacco cut filler and various alternative tobacco products was developed, optimized and fully validated. The method LOD was 1 ng/ mL (S/N = 3.7) and LOQ was 2.5 ng/mL (S/N=10.5). The method had a ...
  7. Beitr. Tabakforsch. Int./Contrib. Tob. Research, 2009, 23-6, p. 377-83., ISSN.0173-783X

    The influence of a humectant on the retention by humans of solanesol from cigarette smoke. (Part 2. Glycerin)

    MOLDOVEANU S.C.; COLEMAN W.M. III
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    Two common humectants are used as additives in the cigarette manufacturing process, propylene glycol (PG) and glycerin. The humectants may influence the deposition of cigarette smoke in the human respiratory tract by affecting the hygroscopic properties ...