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8 results

  1. Beitr. Tabakforsch. Int./Contrib. Tob. Research, 2004, 21-4, p. 240-9., ISSN.0173-783X

    The effect of inhalation volume and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking

    ARMITAGE A.K.; DIXON M.; FROST B.E.
    Sycamore Lodge, Abbey Road, Knaresborough, North Yorkshire, UK
    The influence of inhalation depth and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on nicotine uptake was studied in ten cigarette smokers. In a first series of experiments, the subjects took...
  2. CORESTA Meeting, Smoke Science/Product Technology, Stratford-upon-Avon, 2005, SSPT 36

    The retention of smoke constituents in the human respiratory tract

    BAKER R.R.; DIXON M.
    British American Tobacco, Group R&D, Southampton, UK; British American Tobacco, Globe House, London, UK
    Measurements on the retention of cigarette smoke constituents in the human respiratory tract have been undertaken for more than 100 years. The first studies on nicotine retention were begun by Lehmann in Germany in 1903 and published in 1908. The...
  3. Beitr. Tabakforsch. Int., 2000, 192, p. 103-13., ISSN.0173-783X

    On the transfer of nicotine from tobacco to the smoker. A brief review of ammonia and "pH" factors

    DIXON M.; LAMBING K.; SEEMAN J.I.
    British American Tobacco, Group R&D, Southampton, UK
    A brief review is presented of the scientific literature on the effects of ammonia compounds, when used as tobacco additives, on the smoke chemistry and bioavailablity of nicotine. The review concludes that ammonia compounds used in the manufacture...
  4. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 169-70, ST24

    The effect of inhalation volume and blend additives on nicotine retention and uptake

    MARINER D.C.; ARMITAGE A.K.; DIXON M.; HIGENBOTHAM T.; SINCLAIR N.M.
    British American Tobacco, Group R&D, Southampton, UK
    It has been suggested that as 'tar' and nicotine deliveries from cigarettes have been reduced by the Tobacco Industry, in line with regulations and agreements with national governments, smokers have inhaled deeper to achieve more efficient uptake of...
  5. CORESTA Meeting, Smoke/Technology, Hamburg, 1997, ST08

    Measurement of puffing behaviour in lights and ultra-lights cigarette smokers with ventilation holes partially and fully blocked

    REEVES N.; DIXON M.; HILTON D.C.; AYYA N.; ST. CHARLES F.K.
    British American Tobacco, Group R&D, Southampton, UK
    This study was conducted to assess alterations in puffing behaviour amongst lights (10 mg), high ultra lights (5mg) and low ultra lights (1-3mg) smokers smoking their own brands with none, half and all the ventilation holes blocked. In the...
  6. CORESTA Meeting, Smoke/Technology, Vienna, 1995, ST19

    The measurement of human smoking behaviour and the influence of changes in behavioural parameters on mainstream smoke deliveries

    REEVES N.; DIXON M.
    British American Tobacco, Group R&D, Southampton, UK
    The volumes, durations and frequencies of puffs taken by smokers frequently differ from those used in standard machine smoking regimes. Many factors can influence human smoking parameters, for example, anatomical factors and cigarette design factors...