Search Results

25 results

  1. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 33

    Assessment of exposure biomarkers in U.S. consumers of snus, moist snuff, cigarettes, and dual use

    CARAWAY J.W.; JONES B.A.; CHEN P.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    Biomarkers of exposure (BoE) to constituents in tobacco products and tobacco smoke were assessed in adult, U.S. tobacco consumers who participated in a multi-center, cross-sectional study. A total of 320 subjects (267 males/53 females) were enrolled in ...
  2. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 30

    Consumption patterns and biomarkers of exposure in cigarette smokers switched to snus, various dissolvable tobacco products, dual use, or tobacco abstinence.

    KRAUTTER G.R.; CHEN P.X.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Camel SNUS and dissolvable tobacco Sticks, Strips and Orbs are smokeless products containing lower levels of most tobacco-related toxicants associated with cigarette smoke. This trial investigated short-term changes in product usage and biomarkers of ...
  3. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 27

    Comparison of cigarette smoking to dual use of cigarettes with Camel strips, camel sticks, or Camel snus

    ROUND E.K.; LEE L.C.; BOWMAN S.A.; HARGER K.M.; HEFNER T.M.; MATHEWS M.M.; NELSON P.R.; SLATER A.M.; STILES M.F.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    A series of studies were conducted to evaluate dual use (DU) of cigarettes with Camel Strips (Strips), Camel Sticks (Sticks), or Camel SNUS (CS) by adult smokers in their natural environment. Subjects smoked normally for one week (baseline). Over three ...
  4. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 71

    Consumption patterns and biomarkers of exposure in cigarette smokers switched to dissolvable tobacco (Camel Orbs), dual use, or tobacco abstinence.

    KRAUTTER G.R.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, Winston Salem, NC, USA
    Camel Orbs (Orbs) are comprised of finely-milled tobaccos and food-grade ingredients compressed into a small oval form intended to be ingested. This trial investigated short-term changes in product usage and biomarkers of exposure when adult smokers ...
  5. CORESTA Congress, Edinburgh, 2010, SS 02; TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 34

    A clinical trial of cardiovascular disease biomarkers in adult smokers and moist snuff consumers. Part I: study design, subject selection and cohort characterization

    JONES B.A.; BROWN B.G.; LEE L.C.; HEAVNER D.L.; STEICHEN T.J.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    A single site, three cohort, age-stratified, cross-sectional study was conducted in the US in subjects who were exclusive cigarette smokers (n=60), exclusive moist snuff consumers (n=48), and non-consumers of tobacco (n=60) to identify potential CVD ...
  6. CORESTA Congress, Edinburgh, 2010, SS 03; TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 35

    Cardiovascular disease biomarkers study, Part II: Tobacco-related biomarkers of exposure in exclusive cigarette smokers, exclusive moist snuff consumers, and non-consumers of tobacco.

    BROWN B.G.; JONES B.A.; LEE L.C.; HEAVNER D.L.; STEICHEN T.J.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    A CVD biomarkers study conducted in the US measured putative tobacco-related biomarkers in three exclusive cohorts: cigarette smokers, moist snuff consumers and non-consumers of tobacco. Subjects were generally healthy males between the ages of 26-49. ...
  7. CORESTA Congress, Edinburgh, 2010, SS 04; TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 36

    Cardiovascular disease biomarkers study, Part III: Tobacco-related biomarkers of effect in exclusive cigarette smokers, exclusive moist snuff consumers, and non-consumers of tobacco

    NORDSKOG B.K.; BROWN B.G.; JONES B.A.; HEAVNER D.L.; STEICHEN T.J.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    A three cohort, age-stratified cross-sectional study was conducted in the U.S. in cigarette smokers (n=60), moist snuff consumers (n=48) and non-consumers of tobacco (n=60) to evaluate several known cardiovascular biomarkers of effect. Subject enrolment ...
  8. CORESTA Congress, Edinburgh, 2010, SSPTPOST 13; TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 08

    Clinical methodology and results for physiological assessments including flow-mediated dilation, carotid intima-media thickness, ankle brachial index, spirometry, and expired carbon monoxide in exclusive cigarette smokers, exclusive moist snuff consumers and non-consumers of tobacco

    BROWN B.G.; JONES B.A.; NORDSKOG B.K.; HEAVNER D.L.; STEICHEN T.J.; BORGERDING M.F.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    Several physiological assessments have been reported in the literature as measures for detecting, predicting and monitoring cardiovascular disease (CVD). These non-invasive techniques were investigated in three exclusive all male cohorts (cigarette ...