Search Results

12 results

  1. CORESTA Congress, Online, 2020, Agronomy/Phytopathology Groups, AP 27

    Three-year N-nitrosonornicotine data for stable reduced converter (SRC) dark tobacco crop

    LION K.; LUSSO M.; ADAMS A.; MORRIS W.; DAVIS G.
    Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    During the past several decades, substantial efforts have been made by the tobacco industry and academic institutions to reduce NNN levels and its precursor nornicotine in tobacco products. Research on the mechanism of nornicotine formation led to...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 49 (also presented at TSRC 2019)

    Nicotine variability of low nicotine cultivars versus normal nicotine cultivars

    LION K.; ADAMS A.; MORRIS W.; BROWN E.; IRVING B.; LUSSO M.; XU D.
    Altria Client Services LLC, Product Design & Maintenance, Richmond, VA, U.S.A.
    Nicotine is the most abundant alkaloid in cultivated tobacco (Nicotiana tabacum), typically constituting more than 90 % of total alkaloids. Recently, the U.S. Food and Drug Administration (FDA) issued an Advance Notice of Proposed Rulemaking (ANPRM)...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 071 (also presented at CORESTA SSPT2019)

    Nicotine variability of low nicotine cultivars versus normal nicotine cultivars

    LION K.; ADAMS A.; MORRIS W.; BROWN E.; IRVING B.; LUSSO M.; XU D.
    Altria Client Services, Richmond, VA, USA
    Nicotine is the most abundant alkaloid in cultivated tobacco (Nicotiana tabacum), typically constituting more than 90% of total alkaloids. Recently, the U.S. Food and Drug Administration (FDA) issued an Advance Notice of Proposed Rulemaking (ANPRM)...
  4. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 25

    2017 stable reduced converter (SRC) dark tobacco crop

    LION K.; LUSSO M.; ADAMS A.; MORRIS W.; XU D.; WAREK U.; STRICKLAND J.A.
    Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    On January 23, 2017, FDA published “Tobacco Product Standard for N-nitrosonornicotine Level in Finished Smokeless Tobacco Products” in which they proposed an NNN ceiling of 1.0 ppm (DWB) through the end of product shelf life. During the past several...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 07

    NNN levels in stable reduced converter (SRC) and low converter (LC) lines cured under conditions that favor NNN formation

    LUSSO M.F.; LION K.E.; ADAMS A.; MORRIS W.; WAREK U.; STRICKLAND J.A.
    Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.
    N-nitrosonornicotine (NNN), a tobacco specific nitrosamine (TSNA) found in cured leaf, filler and smoke, is formed by nornicotine nitrosation. We previously demonstrated a ~75 % reduction of cured leaf NNN content in Burley and dark tobaccos having...
  6. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 071

    NNN levels in stable reduced converter (SRC) and LC lines cured under conditions that favor NNN formation

    LUSSO M.F.; LION K.E.; ADAMS A.; MORRIS W.; WAREK U.; STRICKLAND J.A.
    Altria Client Services, Richmond, VA, USA
    N-nitrosonornicotine (NNN), a tobacco specific nitrosamine (TSNA) found in cured leaf, filler and smoke, is formed by nornicotine nitrosation. We previously demonstrated a ~75% reduction of cured leaf NNN content in burley and dark tobaccos having...
  7. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 17

    Tobacco specific nitrosamine (TSNA) levels of the U.S. domestic Burley crop and their relationship with relative humidity conditions during curing

    LION K.; LUSSO M.; MORRIS W.; HART F.
    Altria Client Services Inc., Research, Development & Engineering, Richmond, VA, U.S.A.
    From 2010 to 2014, Altria Client Services conducted a sampling program designed to evaluate tobacco specific nitrosamine (TSNA) levels in the U.S. domestic Burley crop. A representative number of bales from four distinct U.S. Burley growing regions...
  8. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 20

    N-nitrosonornicotine (NNN) level in lamina of experimental Burley isogenic lines bred to have stable low nornicotine content and cured under conditions favorable for TSNA formation

    LUSSO M.; LION K.; MORRIS W.; ADAMS A.
    Altria Client Services Inc., Research, Development & Engineering, Richmond, VA, U.S.A.
    N-nitrosonornicotine (NNN) is a tobacco specific nitrosamine (TSNA) identified in cured tobacco leaf and smoke. NNN is formed through nitrosation of the tobacco alkaloid nornicotine by the nitrosating agent nitrite. Nitrite is derived from reduction...
  9. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 87

    From seed to smoke: N-nitrosonornicotine levels in blended cigarettes containing Burley or flue-cured tobacco stable for low nornicotine content

    LUSSO M.(1); LION K.(1); ADAMS A.(1); LEWIS R.S.(2); MORRIS W.(1); DAVIS G.(1)
    (1) Altria Client Services Inc., Research, Development & Engineering, Richmond, VA, U.S.A.; (2) North Carolina State University, Crop Science Department, Raleigh, NC, U.S.A.
    N-nitrosonornicotine (NNN) is a tobacco specific nitrosamine (TSNA) identified in cured tobacco leaf and smoke. Previous work demonstrated that by stabilizing a low level of the precursor nornicotine in Burley tobacco, the level of NNN in cured leaf...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 25

    From seed to smoke: N-nitrosonornicotine (NNN) level in smoke is significantly reduced in experimental Burley isolines bred to have stable low nornicotine content

    HAYES A.(1); LEWIS R.(2); LUSSO M.(1); LION K.(1); ADAMS A.(1); MORRIS W.(1)
    (1) Altria Client Services Inc., Research, Development & Engineering, Richmond, VA, U.S.A; (2) North Carolina State University, Department of Crop Science, Raleigh, NC, U.S.A.
    N-nitrosonornicotine (NNN) is one of several tobacco specific nitrosamines (TSNAs) identified in cured tobacco leaf and smoke. Previous work has demonstrated that by stabilizing a low level of the precursor nornicotine, the level of NNN in cured leaf...