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6 results

  1. CORESTA Congress, Kyoto, 2004, SS 01

    Individual variations in cigarette mainstream smoke biomarkers of exposure

    DOOLITTLE D.J.; SMITH C.J.; MORTON M.J.; BOMBICK D.W.; BROWN B.G.; HEAVNER D.L.; MORGAN W.T.; OGDEN M.W.; ROBINSON J.H.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Biomarkers of tobacco smoke exposure were measured in urine and buccal cells from 56 smokers of full-flavor low 'tar' (FFLT) cigarettes to evaluate the degree of individual variation. Biomarkers were measured while each individual smoked their usual...
  2. CORESTA Meeting, Smoke/Technology, Xian, 2001, ST 04

    The use of in vitro short term tests to evaluate progress toward reducing the toxicity of cigarette smoke

    DOOLITTLE D.J.; BOMBICK D.W.; BOMBICK B.R.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    A number of tobacco companies are actively pursuing the development of cigarettes with the potential to reduce the risks associated with smoking. Despite decades of debate, the scientific community still lacks a consensus concerning what cigarette...
  3. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 168, ST23

    Biological studies on smoke condensates from cigarettes made with low nitrosamine flue-cured tobacco

    DOOLITTLE D.J.; AVALOS J.T.; BOMBICK B.R.; PUTNAM K.P.; BOMBICK D.W.; NESTOR T.B.; GENTRY J.S.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    R. J. Reynolds Tobacco Company recently developed a process for flue-curing tobacco that results in substantially lower concentrations of tobacco-specific nitrosamines. The technology is based on the use of heat exchangers instead of direct-fired...
  4. Bull. Spec. CORESTA Congress, Yokohama, 1996, p. 97, APST2

    Environmental room human physiology study using fresh diluted sidestream cigarette smoke

    SMITH C.J.; BOMBICK D.W.; MCKARNS S.C.; MORGAN W.T.; DOOLITTLE D.J.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Twenty healthy "never-smoking" subjects (ten males and ten females, ages 21-50) participated in a five-day environmental chamber study to determine if exposure to a moderately high level of cigarette smoke would alter indices related to urinary...