Search Results

51 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 27

    Next generation product aerosol bubbled extracts show little to no effect in high content screening endpoints when compared to cigarette smoke bubbled extracts

    TRELLES STICKEN E.(1); WIECZOREK R.(1); BODE L.M.(1); SIMMS L.(2); STEVENSON M.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), BioToxLab, Hamburg, Germany; (2) Imperial Tobacco Limited, In vitro Research, Bristol, U.K.
    Tobacco-based and tobacco-free next generation products (NGPs) are understood to be a less harmful alternative to conventional combustible cigarettes. The objective of this study was to compare the in vitro biological response of cigarette smoke...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 37

    Use of cell media nicotine concentration as a marker to predict cells surface deposited nicotine in transwells after fresh smoke/aerosol exposure

    WIECZOREK R.(1); TRELLES STICKEN E.(1); BODE L.M.(1); SIMMS l.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Imperial Tobacco Limited, Bristol, U.K.
    Exposure of organotypic 3D lung models at the air liquid interface (ALI) to fresh whole smoke/aerosol provides a more human relevant exposure assessment of combustible cigarettes and e-vapour products. The aim of this study is to present a method...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 56

    Perceptions of the relative harm of electronic cigarettes compared with smoking in the U.S.A.: analysis of the Population Assessment of Tobacco and Health (PATH) study data, 2013-2016

    O’CONNELL G.(1); WALELE T.(1); CAHOURS X.(2); THOMPSON J.(1); VERRON T.(2)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) SEITA - Imperial Brands, Paris, France
    Electronic cigarettes (e-cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the relative risk of these...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 58

    A consortium approach for consumer-reported outcome measures to assess tobacco- and nicotine-containing products

    ACQUADRO C.(1) on behalf of the CORESTA CROM Task Force: AYALA-FIERRO F.(2); BLACK R.(3); CAHOURS X.(4); CHREA C.(5); CURTIN G.(6); GILES L.(7); McCAFFREY S.(3); PARK C.H.(8); PRASAD K.(9); SHERWOOD N.(10); SHIFFMAN S.(11); SMITH J.(6); SPIES E.(5)
    (1) Mapi Research Trust, Lyon, France; (2) ITG Brands, Greensboro, NC, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) SEITA - Imperial Brands, Paris, France; (5) Philip Morris Products S.A., Neûchatel, Switzerland; (6) RAIS, Winston-Salem, NC, U.S.A.; (7) JT Int'l SA, Genève, Switzerland; (8) KT&G Research Institute, Daejeon, Republic of Korea; (9) British American Tobacco, Southampton, U.K.; (10) Neil Sherwood Consulting, Commugny, Switzerland; (11) Pinney Associates, Pittsburgh, PA, U.S.A.
    In the tobacco space, consumer-reported outcome measures (CROM) are essential for understanding motivations, subjective effects, and behavior. Such measures have become particularly important with the advent of candidate modified risk tobacco...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 65; CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 15

    Analysis of mainstream cigarette smoke constituents prioritized by the World Health Organization in a core collection of tobacco accessions: variability and correlations

    CAHOURS X.(2); JULIO E.(1); VERRON T.(2); DORLHAC DE BORNE F.(1)
    (1) SEITA - Imperial Brands, Leaf Research, Bergerac, France; (2) SEITA - Imperial Brands, Scientific Research, Paris, France
    Among the different strategies proposed for tobacco regulation, the WHO study group on Tobacco Product Regulation (TobReg) has proposed mandating ceilings on smoke constituents. These constituents were selected according to their potential toxicity,...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 07 (also presented at TSRC 2017)

    Physical characteristics of handmade premium cigars: specifications and consequences of specifications

    TEILLET B.; VERRON T.; COLARD S.
    SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France
    Handmade premium cigars consist of natural and heterogeneous leaves rolled by hand to a given dimension. This traditional making process is performed by people (rollers) with considerable experience and training. The rollers adapt their technique,...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 22

    Estimation of e-cigarette aerosol yields based on puff duration

    JULIEN R.(1); TSCHIERSKE N.(2); VARIGNON B.(1); TROUDE V.(1); DESTRUHAUT S.(1); WALELE T.(3); COLARD S.(1); CAHOURS X.(1)
    (1) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    There are regulatory requirements in quantifying and comparing the emission levels of major and minor aerosol constituents from e-cigarettes. Up until the recent publication in 2015 of CORESTA Recommended Method (CRM) No. 81 - "Routine Analytical...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 37

    Nicotine reduction: use of a modelling approach to evaluate unintended consequences, a focus on illicit trade

    GUO M.; VERRON T.; CAHOURS X.; COLARD S.
    SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France
    In 2015, the WHO TobReg issued an advisory note recommending a strategy of reducing nicotine in tobacco to substantially lower levels. The authors considered that regulation of nicotine levels would lead to a decrease of smoking prevalence. In their...