Search Results

120 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 51

    Genetic and biochemical analysis of very low nicotine tobacco leaf

    KUDITHIPUDI C.(1); GOVINDARAJULU R.(2); BHUIYAN N.(2); SHEN Y.(1); XU D.(1)
    (1) Altria Client Services LLC, VA 23219, U.S.A.; (2) Eurofins Lancaster Laboratories, c/o Altria Client Services LLC, Richmond, VA, U.S.A.
    Recently, the U.S. Food and Drug Administration issued an advance notice of proposed rulemaking to obtain information for consideration in developing a tobacco product standard to set the maximum nicotine level in cigarette filler. Tobacco industry and ...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 038

    Optimization and comparison of 2,4-dinitrophenylhydrazine (DNPH) derivatization conditions for the determination of carbonyl compounds

    JEONG L.(1); MILLER, J.H., IV(2); SHAH N.(2)
    (1) Eurofins Lancaster Laboratories, Richmond, VA, USA; (2) Altria Client Services, Richmond, VA, USA
    FDA’s Premarket Tobacco Product Application (PMTA) draft guidance for Electronic Nicotine Delivery Systems (ENDS) recommends analysis of four carbonyls in e-liquids and aerosols- Formaldehyde, Acetaldehyde, Acrolein and Crotonaldhyde. There are two ...
  3. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 03

    Transcriptomic and metabolomic analysis of very low nicotine tobacco lines

    KUDITHIPUDI C.(1); SHEN Yanxin(1); GOVINDRAJULU R.(2); XU Dongmei(1); WAREK U.(1); STRICKLAND J.A.(1)
    (1) Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.; (2) Eurofins Lancaster Laboratories, c/o Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.
    Nicotine is the most abundant alkaloid in cultivated tobacco (Nicotiana tabacum), typically constituting more than 90 % of total alkaloids. Recently, the U.S. Food and Drug Administration issued an advance notice of proposed rulemaking to obtain ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 29 (also presented at TSRC 2018)

    Modification of standardized methods for the measurement of nicotine in very low nicotine content cigarettes

    BROWN A.P.(1); LIU Hui(2); MANSON K.(2); MELVIN M.S.(1); PIEROTTI J.(2); PITHAWALLA Y.B.(1); SMITH J.H.(1); STUTT K.(2); WAGNER K.A.(1)
    (1) Altria Client Services LLC, Richmond, VA, U.S.A.; (2) Eurofins Lancaster Professional Scientific Staffing, Richmond, VA, U.S.A.
    In March 2018, the U.S. Food and Drug Administration (FDA) issued an advanced notice of proposed rulemaking (ANPRM) for a nicotine product standard that would limit the amount of nicotine in combusted tobacco products. FDA requested comments regarding ...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 013

    Method development for pH analysis of ends aerosol and e-liquid

    HEFNER T.(1); ST. CHARLES F.K.(2); ANDERSON J.(3)
    (1) R.J. Reynolds Tobacco Company, Winston Salem, NC, USA; (2) St.Charles Consultancy, Winston Salem, NC, USA; (3) Eurofins Lancaster Labs, Winston Salem, NC, USA
    E-liquids are hygroscopic, non-aqueous liquids containing a small amount of water (~3-15%). When the pH of a non-aqueous liquid is measured using conventional methods and calibration buffers, the value can only be regarded as an "apparent pH". ...
  6. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 033

    Water analysis by volumetric Karl Fischer titration using direct heating and transfer to the Karl Fischer titrator

    STOGNER D.C.; BENNER D.N.; STEVENSON B.; ADAMS C.; CHOUCHANE S.
    Eurofins Lancaster Laboratories PSS, Winston-Salem, NC, USA
    Tobacco and tobacco related products typically have been analyzed for water content by extracting into anhydrous methanol and then manually injecting into the Karl Fischer titrator. An alternate method has been developed whereby a sample is weighed into a ...
  7. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 035

    Determination of select leachable compounds in electronic cigarette aerosol and liquid by LCMSMS

    RASHMAWI K.J.; SPANN N.; PORTER A.; ADAMS C.; CHOUCHANE S.
    Eurofins Lancaster Laboratories PSS, Winston-Salem, NC, USA
    Polymeric materials used in the manufacturing of electronic cigarette cartridges may contain compounds that have the potential to leach into the liquid or the aerosol of electronic cigarettes. A method was developed and validated for the determination of ...
  8. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 041

    Analysis of tobacco specific nitrosamines in electronic cigarette liquid by LCMSMS

    SPANN N.D.; SEAMANS A.; ADAMS C.J.; CHOUCHANE S.
    Eurofins Lancaster Laboratories PSS, Winston-Salem, NC, USA
    A new method was needed to analyze low-level TSNA concentrations in electronic cigarette liquid. This proved difficult with the various flavored matrices, however the method was developed to accurately quantitate TSNAs as low as 50 parts per trillion for ...