CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, STPOST 24
Toxic insult to rat precision cut lung slices increases tissue cytokine levels and activation of macrophages, and causes acute damage, while prolonged insult may lead to increased deposition of collagen – a marker of fibrosis
Advanced In Vitro, LLC, Frederick, MD, U.S.A.
The use of in vitro or ex vivo models is intended to provide meaningful data that will identify or predict the adverse effects of tissue exposure. Precision-cut lung slices (PCLS) are used as a model that retains the heterogenous population of cells...