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10 results

  1. Beitr. Tabakforsch. Int./Contrib. Tob. Research, 2001, 19-7, p. 361-79, ISSN.0173-783X

    Studies of polycyclic aromatic hydrocarbons in cigarette mainstream smoke: identification, tobacco precursors, control of levels: A review

    RODGMAN A.
    Alan RODGMAN, 2828 Birchwood Drive, Winston-Salem, North Carolina, 27103-3410, USA
    During the period of tobacco smoke research from the early 1950s to the mid-1960s it was repeatedly asserted that a) tobacco and many tobacco components were involved in the pyrogenesis of polycyclic aromatic hydrocarbons (PAHs), several of which were ...
  2. Beitr. Tabakforsch. Int./Contrib. Tob. Research, 2002, 20-2, p. 83-103., ISSN.0173-783X

    Some studies of the effects of additives on cigarette mainstream smoke properties. I. Flavorants

    RODGMAN A.
    Alan RODGMAN, 2828 Birchwood Drive, Winston-Salem, North Carolina, 27103-3410, USA
    Examination of extensive laboratory data collected during the past four decades, particularly considerable unpublished data generated between the mid-1950s and the late 1970s, indicates that none of the materials used as flavorants on smoking tobacco ...
  3. CORESTA Congress, New Orleans, 2002, APST 03

    Does smoking of ultra-low 'tar' cigarettes result in reduced intake of 'tar' and nicotine?

    ROBINSON J.H.; STILES M.F.; DAVIS R.; EDWARDS D.; PRITCHARD W.; MORGAN W.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    NCI Monograph 13, "Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine," concludes that smoking of ultra-low 'tar' cigarettes does not offer the consumer any benefit in terms of reduced intake ...
  4. CORESTA Congress, New Orleans, 2002, ST 09

    The relative toxicity of substituted phenols reported in cigarette mainstream smoke

    SMITH C.J.; PERFETTI T.A.; MORTON M.J.; RODGMAN A.; GARG R.; SELASSIE C.D.; HANSCH C.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    Cigarette mainstream smoke (MS) contains a number of structurally diverse substituted phenols. Recent quantitative structure activity relationship (QSAR) studies of phenols show that substituted phenols with electron-releasing groups can form potentially ...
  5. CORESTA Congress, New Orleans, 2002, ST 15

    Biomarkers of tobacco smoke exposure: Comparison between smokers and nonsmokers

    BROWN B.; HEAVNER D.L.; BOMBICK D.W.; RICHARDSON J.; DAVIS R.; BYRD G.; CONNELL V.; MORTON M.J.; OGDEN M.W.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    Twenty subjects participated in a pilot study to investigate the association between tobacco smoke intake and several biomarkers. Study endpoints included biomarkers for nicotine, benzene, acrolein, tobacco-specific nitrosamines (TSNA), polycyclic ...
  6. CORESTA Congress, New Orleans, 2002, ST 34

    On the development of a very rapid gas chromatographic method for the analysis of high molecular weight hydrocarbons in cigarette smoke

    COLEMAN W.M. III; GORDON B.M.
    R.J. Reynolds Tobacco Company, Winston Salem, NC, USA
    A very rapid, Flash/GC, quantitative method for the analysis of high molecular weight saturated hydrocarbons in cigarette smoke has been developed. The method was fast, accurate and precise. Sample turn around times were approximately 6 minutes, with an ...
  7. CORESTA Congress, New Orleans, 2002, STPOST 05

    Changes in free levels of oxidative DNA damage/repair products in the alveolar fluid of smokers after switching to Eclipse, a cigarette that primarily heats rather than burns tobacco

    DOOLITTLE D.J.; BROWN B.; MATSON W.; BOGDANOV M.; RENNARD S.; ROMBERGER D.; MANOUILOVA L.; XIANGDE L.
    R.J. Reynolds Tobacco Company, Winston Salem, NC, USA
    Oxidative DNA damage has been implicated in aging, carcinogenesis, heart disease, and neurodegenerative diseases. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a principal stable marker of hydroxyl radical damage to DNA. Tobacco smoking has been shown to ...