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258 results

  1. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 10

    Modular new product development in highly dynamic markets

    KÜCHENHOF J.(1); NIEBUHR G.(2); SCHMIDT R.(2); KESSLER M.(2); KRAUSE D.(1)
    (1) Hamburg University of Technology, TUHH, Institute for Product Devcelopment and Mechanical Enginnering Design (PKT), Hamburg, Germany; (2) Hauni Maschinenbau GmbH, Dev. Vaping Technologies, Hamburg, Germany
    The implementation of a new approach always poses some organizational challenges but can also offer unrecognized opportunities. The Integrated PKT-approach for Development of Modular Product Families has been successfully implemented to reduce the...
  2. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 12

    Thermal behaviour of tobacco pads for aerosol generation

    JAMALI A.(1); BÄUMKER E.(1); SABERI M.(1); PELZ U.(1); SHEER C.(2); KESSLER M.(2); SCHMIDT R.(2); GOLDSCHMIDTBÖING F.(1)
    (1) University of Freiburg, IMTEK, Design of Microsystems, Freiburg, Germany; (2) Hauni Maschinenbau GmbH, Vaping Technologies, Hamburg, Germany
    Aerosol generation by heating tobacco to temperatures well below the burning point is one attempt to reduce the health risk of tobacco products. However, due to the poor thermophysical properties of tobacco, it takes a considerable amount of time and...
  3. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 13

    In vitro biological assessment of nicotine administration efficiency of a prototypic ENDS with a novel volumetric heater

    MIRDOGAN A.
    Hauni Maschinenbau GmbH, Hamburg, Germany
    Due to the growing awareness of the adverse health effects of smoking tobacco and repeated recommendations from health experts, smokers try to quit using nicotine replacement therapies. This leads to an interest in electronic nicotine delivery...
  4. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 17

    The dos and don’ts of non-targeted screening by LC–HRAM-MS for chemical characterization of smoke-free products

    WACHSMUTH C.; ARNDT D.; BUCHHOLZ C.; BENTLEY M.; GOUJON-GINGLINGER C.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    Liquid chromatography coupled to high-resolution accurate-mass spectrometry (LC–HRAM-MS)-based non-targeted screening (NTS) is a key methodology for characterizing the chemical composition of complex matrices. It enables simultaneous identification...
  5. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 18

    Computer-assisted structure identification (CASI) for high-throughput identification of small molecules by GC×GC–HRAM-TOFMS

    KNORR A.; ALMSTETTER M.; MARTIN E.; CASTELLON A.; POSPISIL P.; BENTLEY M.; GOUJON C.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    Compound identification is widely recognized as a major bottleneck in modern metabolomic approaches and high-throughput non-targeted characterization of complex matrices. An automated platform CASI (computer-assisted structure identification) was...
  6. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 19

    Non-targeted chemical characterization of complex matrices by nominal- and high-resolution accurate-mass GC×GC–TOFMS

    ALMSTETTER M.; KNORR A.; RHOUMA M.; MARTIN E.; CASTELLON A.; POSPISIL P.; BENTLEY M.; GOUJON C.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    Comprehensive chemical characterization is an important element in the development of heat-not-burn products. Beyond the challenge of developing powerful analytical methods with sufficient chromatographic and spectral resolution, it is essential to...
  7. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 21

    Untargeted chemical characterization of the aerosol generated by a heated tobacco product

    BENTLEY M.; ALMSTETTER M.; ARNDT D.; KNORR A.; MARTIN E.; POSPISIL P.; MAEDER S.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    In contrast to quantitative analysis, where chemical constituents of interest are targeted to the exclusion of all others, an untargeted approach considers indiscriminate determination of all analytes relevant to a specific chemical space. A...
  8. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 24

    Dos and don’ts in the design of indoor air quality studies on smoke-free products

    MITOVA M.I.; GOUJON-GINGLINGER C.; GOMEZ LUESO M.; ROTACH M.; MAEDER S.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    Indoor air quality (IAQ) studies on smoke-free products (SFPs), such as electrically heated tobacco products (EHTPs) and e-vapour products (EVPs), have demonstrated substantial reduction of environmental emissions relative to cigarette smoking. IAQ...
  9. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 26

    Comparative risk assessment of heated tobacco product and electronic cigarette aerosols with cigarette smoke based on cancer potency and margin of exposure

    RODRIGO G.; JACCARD G.; TAFIN DJOKO D.; KORNELIOU A.; ESPOSITO M.; BELUSHKIN M.
    Philip Morris Products S.A., PMI R&D, Neuchâtel, Switzerland
    An average reduction of more than 90 % in concentrations of harmful and potentially harmful constituents (HPHCs; among given lists) has been observed in the aerosols of commercial heated tobacco products (HTPs) and electronic cigarettes (ECs)...
  10. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, STPOST 05

    A screening method by gas chromatography–mass spectrometry for the quantitation of 33 aerosol constituents from a heat-not-burn tobacco product

    HOFER I.; GAUTIER L.; CORTES SAUTEUR E.; DOBLER M.; PYTHON A.; O’REILLY C.; GISI D.; TINGUELY E.; WEHREN L.; GARCÍA FIDALGO E.; CUKURCAM L.; HENNEMANN M.; MATERA R.; ROTA D.; SANTOS CH.; SEQUEIRA C.; EPARS T.
    Philip Morris Products S.A., PMI R&D, Neuchatel, Switzerland
    This screening method allows the quantitation of 33 compounds [phenol, o-cresol, m-cresol, p-cresol, catechol, resorcinol, hydroquinone, 1,3-butadiene, isoprene, benzene, acrylonitrile, toluene, pyridine, styrene, propylene glycol, menthol,...