1. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 31

    Psychometric evaluation of the mCEQ applied to cigarettes and heat-not-burn products in the U.S. and Japan

    SALZBERGER T.(1); CANO S.(2); MAINY N.(3); CHREA C.(3); VANDYKE S.(3); HAZIZA C.(3); WEITKUNAT R.(3); ROSE J.(4)
    (1) University of Economics and Business, Vienna, Austria; (2) Scale Report, Stotfold, U.K.; (3) Philip Morris Products S.A., Neuchatel, Switzerland; (4) Rose Research Center, Raleigh, U.S.A.
    The modified Cigarette Evaluation Questionnaire (mCEQ) is a self-report instrument that assesses the reinforcing effects of smoking cigarettes from a smoker’s perspective. Conceptually, the mCEQ consists of three multi-item and two single-item...
  2. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, ST 06

    Evaluation of a biomarker of oxidative stress: 8-iso-prostaglandin F2α / prostaglandin F2α ratio

    NEWLAND K.(1); MILLER P.(1); FARMEN R.(1); TRAN C.T.(2); HAZIZA C.(2); PICAVET P.(2)
    (1) Celerion, Inc., Lincoln, NE, U.S.A.; (2) Philip Morris Products S.A. (part of Philip Morris International group of companies), Neuchâtel, Switzerland
    It is understood that exposure to free radicals related to tobacco use negatively impacts smoker health. Studies have been performed measuring fatty acid oxidation products (F2-Isoprostanes) in human urine as biomarkers of harm from free radical...
  3. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 20

    Evaluation of a biomarker of oxidative stress: the 8-iso prostaglandin F2α: prostaglandin F2α ratio in human plasma

    MILLER P.(1); NEWLAND K.(1); DZERK A.(1); FARMEN R.(1); TRAN C.T.(2); HAZIZA C.(2); PICAVET P.(2)
    (1) Celerion, Inc., Lincoln, NE, USA; (2) Philip Morris International, Neuchâtel, Switzerland
    F2-isoprostanes have been widely studied as biomarkers of oxidative stress for various indications, including smoking. Since both enzymatic biosynthesis and chemical lipid peroxidation can generate these biomarkers, there are various interpretations...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2011, Graz, STPOST 07

    Evaluation of the diagnostic accuracy of a candidate biomarker to detect use of conventional cigarettes in users of tobacco products that do not burn tobacco

    (1) Clinopsis SA, Concise, Switzerland; (2) Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    Objective: In clinical studies to assess alternative tobacco products that heat rather than burn tobacco, a compliance biomarker is needed to detect the additional use of conventional cigarettes. Standard biomarkers of exposure to cigarette smoke...