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95 results

  1. CORESTA Congress, Sapporo, 2012, Plenary Session, Invited Paper 2

    Molecular mechanisms of smoking induced cardiovascular disease: insights from cellular and animal models

    ZWEIER J.L.
    Davis Heart & Lung Research Institute and the John H. and Mildred C. Lumley Chair in Medicine at the Ohio State University College of Medicine, USA
    This lecture will review how smoking contributes to cause cardiovascular disease and the critical role of endothelial dysfunction in this process. The process by which the critical endothelial-derived relaxing factor, nitric oxide (NO), and the enzyme ...
  2. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 11

    Application of carbon fiber microelectrodes for measurement of kinetic constants of nitric oxide decay in blood

    ZWEIER J.L.; XIAOPING LIU; EL-SHERBINY G.A.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Endogenous nitric oxide (NO) is a potent vasodilator that regulates vascular tone. There is evidence that cigarette smoking increases superoxide production in blood vessels by rapidly inactivating NO. This impaired NO bioavailability is a critical cause ...
  3. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 39

    Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2-d differential in-gel electrophoresis/mass spectrometry

    ZWEIER T.L.; TEWARI A.K.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Cigarette smoke exposure is known to induce chronic obstructive pulmonary disease, atherosclerosis, and several types of cancer in humans and also in animal models. Smoking leads to oxidative stress and inflammation that are important in triggering ...
  4. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 51

    Chronic cigarette smoke exposure induces vascular dysfunction through upregulation of cytoglobin in mouse aorta

    EL-MAHDY M.A.; EL-SHERBINY G.A.; ABDELGHANY T.M.; ZWEIER J.L.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Cigarette smoking is a risk factor for cardiovascular disease. The relationship between smoking and cardiovascular disease results from multiple mechanisms that interact to contribute to several pathological conditions, including vascular dysfunction. In ...
  5. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 52

    Chronic cigarette smoke exposure impairs vascular endothelial function through a tetrahydrobiopterin-dependent mechanism

    ABDELGHANY T.M.; EL-SHERBINY G.A.; EL-MAHDY M.A.; ZWEIER J.L.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Institute, Columbus, OH, USA
    Cigarette smoke exposure (CSE) is one of the major risk factors of cardiovascular disease. Although tobacco smoking is associated with the onset of atherosclerosis, coronary disease, and ischemic heart disease, the precise mechanism by which these ...
  6. CORESTA Congress, Paris, 2006, APOST 09

    Growth, maturation and senescence of Oriental tobacco leaves as affected by ethephon and inhibitors of ethylene biosynthesis

    KARAIVAZOGLOU N.A.; PAPAKOSTA D.K.; SFACIOTAKIS E.M.; DIVANIDIS S.
    Aristotle University of Thessaloniki, and Tobacco Institute, Laboratory of Agronomy, Laboratory of Pomology, Drama, Greece
    Ethylene is a gaseous plant growth regulator that it has long been known to promote fruit ripening and senescence of plant tissues. In contrast, aminoethoxyvinylglycine (AVG) and aminooxyacetic acid (AOA) both inhibitors of ethylene biosynthesis are ...
  7. CORESTA Congress, Paris, 2006, PT 20

    Feature selection from near infrared spectra using genetic algorithms for tobacco blend recognition

    FIGUERES G.; DE SOUZA S.; REYNES C.; SABATIER R.; VIDAL B.
    Altadis Research Centre, Fleury-les-Aubrais, France
    Near infrared reflectance spectroscopy has proved to be very useful for predicting concentrations of chemical compounds in tobacco, classification or pattern recognition of cigarette blends. The resulting measurement of a sample is a whole reflectance ...
  8. CORESTA Congress, Paris, 2006, SS 01

    How representative of the human smoking behaviour would be the new alternative smoking regimes? A first attempt of assessment

    MARCHAND V.; TESSIER C.; DUMERY B.
    Altadis Research Centre, Fleury-les-Aubrais, France
    The ISO or FTC smoking conditions (35 mL- 2 s puffs, 1 puff per minute) have been more and more criticized during the last decade, especially because they would not reflect the human smoking behaviour. Their main objective was not to predict the exact ...
  9. CORESTA Congress, Paris, 2006, SS 13

    A mixture experimental design with six variables and the effects on smoke components:1 - Presentation of this experimental design and of some initial results on physical characteristics of cigarettes and blends

    VIDAL B.; FIGUERES G.; BIESSE J.P.; BREGEON B.; LOUVET F.; MUZELLEC L.
    Altadis Research Centre, Fleury-les-Aubrais, France
    The objective of this paper is to examine the effects of six tobacco components on the chemical and physical characteristics of blends and cigarettes and particularly on the mainstream smoke yields. First of all, we will develop the philosophy of this ...