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41 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2011, Santiago, AP 03

    Lowering TSNAs through nitrite reductase activity

    DAVENPORT S.E.; FORSYTH K.; TULLY L.; LISTER R.; LE LAY P.; MAUNDERS M.; SANCHEZ-TAMBURRINO J.P.
    Advanced Technologies Ltd., Cambridge, UK (holding of British American Tobacco Ltd.)
    Tobacco specific nitrosamines (TSNAs) are compounds in tobacco that have been shown to be carcinogenic. TSNAs are formed by the nitrosation of tobacco alkaloids with the main nitrosating agent believed to be nitrite. High levels of nitrate accumulation ...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2011, Santiago, AP 27

    Tobacco Biotechnology: a tool for business solutions

    SANCHEZ-TAMBURRINO J.P.; EDWARDS K.; JONES L.; DAVENPORT S.E.
    Advanced Technologies Ltd., Cambridge, UK (holding of British American Tobacco Ltd.)
    Over the past 20 years, genetic modification and molecular breeding has been successfully used in many different crops to provide agronomic advantages (i.e., herbicide resistance, insect tolerance). However there are many other areas where it can be used ...
  3. TSRC, Tob. Sci. Res. Conf., 2009, 63, abstr. 39

    The submission of available toxicological information on the ingredients in tobacco products in the European Union

    THIELEN A.; SCHERER G.; HELLER W-D.
    Deutscher Zigarettenverband, Berlin, Germany
    Article 6 of the European Union Tobacco Products Directive 2001/37/EC requires that manufacturers and importers of tobacco products submit a list of all ingredients used in the manufacturing of their tobacco products itemized by type and brand name. It ...
  4. CORESTA Congress, Shanghai, 2008, SSPTPOST 11

    Use of an EpiOralTM human tissue model for testing of substances for oral irritancy in vitro

    JAI T.S.; DELVES S.J.; FAUX S.P.; KUMARAVEL T.S.; NEILSON L.R.; MEREDITH C.
    Advanced Technologies Ltd., Cambridge, UK
    The EpiOralTM tissue model consists of normal human keratinocytes differentiated to form a multilayered tissue. The phenotype is analogous to human oral epithelium in vivo providing the opportunity for in vitro irritancy testing on human tissue. This ...