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  1. Tobacco Science & Technology, 2011, 1, p. 36-42., ISSN.1002-0861

    Caspase-mediated apoptosis of human bronchial epithelial cells induced by crotonaldehyde

    LIU XING-YU(1,2); YANG ZHI-HUA(3); PAN XIU-JIE(3); ZHU MAO-XIANG(3); XIE JIAN-PING(4)
    1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning, P.R. China; 2. Beijing Work Station, Technology Center of Shanghai Tobacco (Group) Corporation, Beijing 101121, P.R. China; 3. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, P.R. China; 4. Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, P.R. China
    In order to assess the health risk of cigarette smoke, crotonaldehyde-induced cell death and its mechanism in BEAS-2B cells were investigated. Cell survival rate, intracellular ATP level, apoptosis rate, cytochrome c released from mitochondria to ...