Tobacco Science & Technology, 2011, 1, p. 36-42., ISSN.1002-0861
Caspase-mediated apoptosis of human bronchial epithelial cells induced by crotonaldehyde
1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning, P.R. China; 2. Beijing Work Station, Technology Center of Shanghai Tobacco (Group) Corporation, Beijing 101121, P.R. China; 3. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, P.R. China; 4. Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, P.R. China
In order to assess the health risk of cigarette smoke, crotonaldehyde-induced cell death and its mechanism in BEAS-2B cells were investigated. Cell survival rate, intracellular ATP level, apoptosis rate, cytochrome c released from mitochondria to ...