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  1. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 26

    Dynamic determination of nicotine and 11 metabolites in brain and blood of rat by simultaneous microdialysis coupled with UHPLC-HRMS

    MAO Jian; SUN Shihao; LU Binbin; LI Peng; LIU Junhui; ZENG Shitong; ZHANG Qidong; CHAI Guobi; XI Hui; ZHANG Jianxun
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    Nicotine is the most specific cigarette smoke component and plays a key role in tobacco addiction. Nicotine dependence based on neuropharmacology effects is closely associated with nicotine metabolism. Although peripheral metabolism of nicotine has...