CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 26
Dynamic determination of nicotine and 11 metabolites in brain and blood of rat by simultaneous microdialysis coupled with UHPLC-HRMS
Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
Nicotine is the most specific cigarette smoke component and plays a key role in tobacco addiction. Nicotine dependence based on neuropharmacology effects is closely associated with nicotine metabolism. Although peripheral metabolism of nicotine has...