Search Results

144 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 25

    Misperception of e-cigarette harm growing among American adults, 2013-2015

    VERRON T.(1); GUO M.(1); VARIGNON B.(1); O'CONNELL G.(2); WALELE T.(2); CAHOURS X.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Fontem Ventures B.V., Amsterdam, The Netherlands
    Electronic cigarettes (e cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. However, the proportion of American adults who perceive e cigarettes to be equally or more ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 52

    Biological test procedure for fresh generated cigarette smoke and e-cigarette aerosols under air-liquid interface (ALI) exposure in 24 and 96 multi-well plates

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    Cigarette smoke and e cigarette aerosol contain particulate matter/liquid droplets in the solid phase as well as volatile substances in the gas phase. Both fractions are of potential toxicological relevance and should be considered when assessing ...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 53

    Use of human derived cell lines to increase the biological relevance of cigarette condensate, non-tobacco materials and e-liquids testing

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    The in vitro testing strategy of tobacco products is mainly based on the testing of extracts from cigarette smoke condensates. An accepted industry wide assay battery has been developed over recent years which delivers reliable results for the ...
  4. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 39

    Identification of genetic determinants controlling cadmium accumulation in tobacco

    BERTRAND J.(1); JULIO E.(2); COTUCHEAU J.(2); DORLHAC DE BORNE F.(2); BERTHOMIEU P.(1)
    (1) UMR de Biochimie et Physiologie Moléculaire des Plantes, INRA/CNRS/Montpellier SupAgro/Université Montpellier, Montpellier, France; (2) Imperial Tobacco Limited, Leaf Research, La Tour, Bergerac, France
    Cadmium is a toxic heavy metal naturally absorbed and accumulated by plants. It is present in tobacco (Nicotiana tabacum) leaves and potentially in the smoke of cigarettes. Reducing the cadmium content in leaves of tobacco plants requires a better ...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 55

    Genetic and functional analysis of va resistance durability to Potato virus Y in tobacco

    JULIO E.(1); MICHEL V.(2); COTUCHEAU J.(1); DORLHAC DE BORNE F.(1); GLAIS L.(3.4); JACQUOT E.(5); DECROOCQ V.(2); CANDRESSE T.(2); GERMAN-RETANA S.(2)
    (1) Imperial Tobacco Limited, Leaf Research, La Tour, Bergerac, France; (2) INRA et Université de Bordeaux, UMR 1332 BFP, BP81, Villenave d’Ornon, France; (3) FN3PT/RD3PT, Paris, France; (4) INRA, UMR1349 IGEPP, Le Rheu, France; (5) INRA-Cirad-Supagro Montpellier, UMR BGPI, Montpellier, France
    Many recessive resistances against potyviruses are mediated by eukaryotic translation initiation factors (eIF4E). In tobacco, the va resistance gene commonly used to control PVY corresponds to a large (almost 1Mb) deletion affecting a copy of eIF4E ...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, APPOST 12

    Di@gnoPlant® Tobacco: a mobile tool to identify tobacco diseases

    BLANCARD D.(1); ARMAND J.M.(1); MARIGNAC E.(2)
    (1) INRA, UMR Santé et Agroécologie de la Vigne, ISVV - IFR103, Villenave-d'Ornon, France; (2) CORESTA, Paris, France
    In order to reduce the use of crop protection agents in the field, the early and reliable identification of diseases and the detection of emergent pests have proven to be crucial stages in plant protection. An early diagnosis enables implementation of the ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 62

    Overview of in vitro methods used to assess e-cigarettes based on “Toxicity Testing in 21st Century” principles

    SIMMS L.(1); STEVENSON M.(1); CZEKALA L.(1); TSCHIERSKE N.(1); WALELE T.(2)
    (1) Imperial Tobacco Ltd, Bristol, U.K.; (2) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    When the National Academies of Sciences released “Toxicity Testing in the 21st Century: A Vision and a Strategy” a new toxicological paradigm was created, focusing on the use of human cell lines and the disruption of key cellular pathways. In keeping with ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 08

    Indoor air quality and surface deposition assessment following use of an open system e-cigarette

    BAUER N.(1); TSCHIERSKE N.(1); O'CONNELL G.(2); CAHOURS X.(3)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands; (3) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France
    Electronic cigarette (e-cigarette) nicotine delivery devices are growing in popularity worldwide. Both regulators and public health organisations are beginning to examine potential implications that exposure to exhaled e-cigarette aerosol may have on non ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 21

    The use of in vitro human biomarkers from relevant primary cell lines, to assess the effects of increasing nicotine concentration in e-liquids

    SIMMS L.(1); STEVENSON M.(1); CZEKALA L.(1); TSCHIERSKE N.(1); BERG E.(2); WALELE T.(3)
    (1) Imperial Tobacco Ltd, Bristol, U.K.; (2) DiscoverX Corporation, Fremont, CA, U.S.A.; (3) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    As part of the ongoing stewardship of electronic cigarettes, and in line with the National Academies of Sciences “ Toxicity Testing in the 21st Century: A Vision and a Strategy ”, Fontem Ventures B.V. have investigated the utility of a series of endpoints ...