Search Results

82 results

  1. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 27

    The research and application of systematic technologies for reducing tobacco specific nitrosamines in tobacco and cigarette smoke

    BAI Ruoshi(1); ZHOU Jun(1); YANG Chunlei(2); SHI Hongzhi(3); LIU Weijuan(4); XU Tongguang(1); MA Yanjun(1); LIU Xingyu(1); YANG Jinpeng(2); WANG Jun(3); ZHANG Jie(1); YANG Zhendong(1); ZHENG Xiaoman(1); ZHANG Chen(1)
    (1) Technical Center of Beijing Cigarette Factory, Shanghai Tobacco Group Co., Ltd, Beijing, P.R. China; (2) Hubei Tobacco Research Institute, Wuhan, P.R. China; (3) Henan Agriculture University, Zhengzhou, P.R. China; (4) Yunnan Reascend Tobacco Technology (Group) Co., Ltd, Kunming, P.R. China
    Reduction of tobacco specific nitrosamines (TSNAs) in tobacco and cigarette smoke is a research hotspot. The systematic technologies for reducing TSNAs in both agricultural and industrial areas were developed and applied. The TSNA levels for the upper and ...
  2. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 28

    Effect of vacuum packaging on the formation of TSNAs in tobacco leaves during storage

    WANG Jun(1); SHI Hongzhi(1); Li Jingjing(1); ZHOU Jun(2); YANG Huijuan(1); BAI Ruoshi(2); ZHANG Chen(2)
    (1) Henan Agricultural University / China National Tobacco Cultivation & Physiology & Biochemistry Research Center / Tobacco Cultivation Key Laboratory of China Tobacco, Zhengzhou, P.R. China; (2) Beijing Cigarette Factory of Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China
    Experiments were carried out to further clarify the effect of NOx on the formation of TSNAs during tobacco storage. Vacuum treatment was used to change the packing method of tobacco leaves, after which the changes of TSNAs after high temperature treatment ...
  3. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 29

    Changes in content of TSNAs and other compounds of different tobacco types during 6-year long-term storage

    ZHANG Mengyue(1); SHI Hongzhi(1); ZHOU Jun(2); DUAN Weidong(3); YANG Huijuan(1); BAI Ruoshi(2)
    (1) Henan Agricultural University, National Tobacco Cultivation & Physiology & Biochemistry Research Center, Zhengzhou, P.R. China; (2) Beijing Cigarette Factory of Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China; (3) China Tobacco Henan Industrial Ltd Co., Zhengzhou, P.R. China
    Samples of flue-cured, Burley and sun-cured tobaccos from different production areas were collected to investigate the changes in content of tobacco specific nitrosamines (TSNAs) by the SPE-LC-MS/MS method during 6-year long term storage under natural ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 13

    Release mechanism of nicotine in heat-not-burn tobacco products

    HUA Qing; ZHENG Saijing; ZHANG Wei; ZHOU Huiming; ZHANG Yichun; LU Wenjie; WU Da; SHEN Yi; LIU Baizhan
    Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    In this paper, the release of nicotine from reconstituted tobacco, on which different amounts of glycerol and water were applied, was investigated at different temperatures. The thermal release behaviour of nicotine from reconstituted tobacco was verified ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 25

    Misperception of e-cigarette harm growing among American adults, 2013-2015

    VERRON T.(1); GUO M.(1); VARIGNON B.(1); O'CONNELL G.(2); WALELE T.(2); CAHOURS X.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Fontem Ventures B.V., Amsterdam, The Netherlands
    Electronic cigarettes (e cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. However, the proportion of American adults who perceive e cigarettes to be equally or more ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 19

    Simultaneous analysis of five tobacco-specific N-nitrosamines in blood plasma of non-smokers and smokers using fully automated online solid phase extraction-liquid chromatography-tandem mass spectrometry

    ZHANG Jie(1); LIU Xingyu(1); BAI Ruoshi(1); YANG Zhendong(1); SHI Bing(2); ZHANG Chen(1); ZHOU Jun(1)
    (1) Beijing Workstation, Technology Center, Shanghai Tobacco Group Co., Ltd of CNTC, Beijing, P.R. China; (2) Army General Hospital of PLA, Beijing, P.R. China
    Tobacco-specific nitrosamines (TSNAs) in cigarette smoke are known as potential carcinogens. 4-(methylnitrosamino)-l-(3-pyridine)-l-butanol (NNAL) and its glycoside derivates are established as biomarkers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone ...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 22

    Simultaneous determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and cotinine in urine of smokers using two-dimensional liquid chromatography/tandem mass spectrometry

    LI Gang; WANG Yangzhong; TAO Liqi; WU Da; YAO Heming; LIU Baizhan
    Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and cotinine are two efficient biomarkers of tobacco-specific carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and nicotine. In this contribution, we developed an effective system of two ...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 23

    Determination of 15 PAHs in mainstream cigarette smoke using concurrent solvent recondensation (CSR) injection combined with GC-MS/MS

    LUO Chen; QI Dawei; TAO Liqi; WU Bingyu; WU Da
    Technology Centre of Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    Concurrent solvent recondensation (CSR) injection technique is known as one of the approaches to fulfill large volume injection for GC. With the advantages of large volume injection, complex steps such as concentration, enrichment and solid-phase ...
  9. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 52

    Biological test procedure for fresh generated cigarette smoke and e-cigarette aerosols under air-liquid interface (ALI) exposure in 24 and 96 multi-well plates

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    Cigarette smoke and e cigarette aerosol contain particulate matter/liquid droplets in the solid phase as well as volatile substances in the gas phase. Both fractions are of potential toxicological relevance and should be considered when assessing ...
  10. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 53

    Use of human derived cell lines to increase the biological relevance of cigarette condensate, non-tobacco materials and e-liquids testing

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    The in vitro testing strategy of tobacco products is mainly based on the testing of extracts from cigarette smoke condensates. An accepted industry wide assay battery has been developed over recent years which delivers reliable results for the ...