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7 results

  1. CORESTA Congress, Shanghai, 2008, SSPTPOST 11

    Use of an EpiOralTM human tissue model for testing of substances for oral irritancy in vitro

    JAI T.S.; DELVES S.J.; FAUX S.P.; KUMARAVEL T.S.; NEILSON L.R.; MEREDITH C.
    Advanced Technologies Ltd., Cambridge, UK
    The EpiOralTM tissue model consists of normal human keratinocytes differentiated to form a multilayered tissue. The phenotype is analogous to human oral epithelium in vivo providing the opportunity for in vitro irritancy testing on human tissue....
  2. CORESTA Congress, Paris, 2006, SS 30

    Human bronchial epithelial cell transcriptome: gene expression changes following acute exposure to whole cigarette smoke in vitro

    PATWARDHAN S.; MAUNDERS H.; PHILLIPS J.; CLACK A.; RICHTER A.
    Advanced Technologies Ltd., Cambridge, UK
    Cigarette smoke is a complex mixture of over 4000 constituents. Its effects on cell biology are poorly understood, partly because whole smoke exposure in vitro is technically challenging. To investigate the effects of smoke on cell signalling and...