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44 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 14 (also presented at TSRC 2017)

    New smoking machine approach for cigarette smoking under intense and ISO 3308 conditions

    ROSE N.; SCHMIDT T.
    Borgwaldt KC GmbH, Hamburg, Germany
    ISO 3308 specifies the definitions and conditions for routine analytical smoking machines, defining the puffing regime as a 35 ml bell shape puff with a 2 s duration taken every 60 s. It also specifies two machine types “A” and “B” dependent on the ...
  2. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 33

    Accurate and reproducible dispensing of patterned picoliter quantities of tobacco extract onto apical surfaces of human 3D reconstructed airway tissues

    BEHRSING H.(1); SADOWSKI N.(1); CONSTANT S.(2); HUANG S.(2); RAABE H.(1)
    (1) Institute for In Vitro Sciences, Inc., Gaithersburg, MD, U.S.A.; (2) Epithelix Sàrl, Geneva, Switzerland
    There is an increasing need for researchers to understand the dynamic aspects of inhaled tobacco product exposure. Exposure-induced events can cause respiratory irritation, sensitisation, and other events that may lead to severe pulmonary disease. ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, STPOST 10

    A new in vitro testing module for the cytotoxic evaluation of e-cigarette vapour

    SCHEFFLER S.(1); DIEKEN H.(1); MOEHLE N.(1); AUFDERHEIDE M.(1); SCHMIDT T.(2)
    (1) Cultex Laboratories GmbH, Hannover, Germany; (2) Borgwaldt KC GmbH, Hamburg, Germany
    The e-cigarette market has recently been booming, and e-cigarettes are often described as “reduced-risk” nicotine products or alternatives to combustible cigarettes. However, no regulations for e-cigarettes are currently in force, so that the quality and ...
  4. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 109

    3d reconstructed human airway models: effect of acclimation conditions on biomarker and inflammatory response following tissue challenge

    BEHRSING H.; RAABE H.A.; SHEEHAN D.W.; SLY E.A.; CURREN R.D.
    Institute for In Vitro Sciences, Gaithersburg, MD USA
    Human reconstructed, 3-dimensional (3D) airway tissues present researchers with organotypic models that consist of heterogenous cell types that more accurately reflect the pulmonary airway in vivo. These in vitro models are now increasingly applied to ...
  5. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 12

    E-cigarette vaping machine vs. conventional smoking machine – a compendium of differences in requirements and technology in regards to ISO 3308

    ROSE N.
    Borgwaldt KC GmbH, Hamburg, Germany
    E-products are a rapidly growing market. Starting with disposable or rechargeable products looking similar to conventional cigarettes, the market changed to more complex products. These so called second and third generation products offer a technical ...