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3 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 52

    Biological test procedure for fresh generated cigarette smoke and e-cigarette aerosols under air-liquid interface (ALI) exposure in 24 and 96 multi-well plates

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    Cigarette smoke and e cigarette aerosol contain particulate matter/liquid droplets in the solid phase as well as volatile substances in the gas phase. Both fractions are of potential toxicological relevance and should be considered when assessing...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 53

    Use of human derived cell lines to increase the biological relevance of cigarette condensate, non-tobacco materials and e-liquids testing

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    The in vitro testing strategy of tobacco products is mainly based on the testing of extracts from cigarette smoke condensates. An accepted industry wide assay battery has been developed over recent years which delivers reliable results for the...
  3. CORESTA Meeting, Smoke Science/Product Technology, Stratford-upon-Avon, 2005, SSPT 24

    Validation of a new smoking machine for the exposure of 96 well cell culture plates to 'native' cigarette mainstream smoke aerosol. Course of action and some in vitro toxicological data

    WIECZOREK R.; RÖPER W.; BURGHART H.
    Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Corporate Responsibility, Hamburg, Germany; Heinrich Burghart Elektro-und Feinmechanik GmbH, Wedel, Germany.
    In order to generate toxicological data of cigarette aerosol different smoke exposure systems have been designed the last years. These machines should simulate smoke exposure conditions comparable to human exposure. Since 1999 we have been optimising...