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138 results

  1. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 54

    Evaluation of gaseous phase nicotine in e-liquid nicotine salts in e-cigarette aerosols

    JONES T.(1,2); KINTNER S.(1,2); ARMWOOD S.(1,2); ILLIDGE B.(3); LU HUANGHAI(3); HARDMAN P.(3); PANI J.(2); RUAN CHUNHAI(1,2)
    (1) ITG Brands, Greensboro, NC, USA; (2) Imperial Brands-Lab Network, Hamburg, Germany; (3) Imperial Brands-Nerudia, Liverpool, UK
    Nicotine is a key component in many e-cigarette formulations and during the vaping process, nicotine exists in both the gaseous phase and aerosol phase. There are two type of vaping techniques- mouth-to lung (MTL) and direct-to-lung (DTL). The...
  2. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 03

    Method development for the analysis of mono-carbonyl compounds in e-vapor products by LC-MS

    ZHU J.; HEREDIA A.; TWEEDY J.; TAYYARAH R.
    ITG Brands and Fontem USA, Greensboro, NC, U.S.A.
    At the 73rd Tobacco Science Research Conference (TSRC), we presented a novel method for quantitation by LC-MS of mono-carbonyl compounds in e-vapor product aerosol samples. The method is simple and robust with good recoveries. We have since extended...
  3. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 10

    The influence of sodium carbonate buffer on TSNAs accumulation and leaf quality during tobacco storage

    LIU Xingyu(1); LIU Deshui(1); MA Li(1); MA Yanjun(1); YANG Zhendong(1); ZHANG Jie(1); LIN Lin(2); BAI Ruoshi(1); ZHOU Jun(1)
    (1) Technology Center, Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China; (2) Beijing Tobacco Quality Supervision and Testing Station, Beijing, P.R. China
    Storage of tobacco leaves is an important stage in tobacco processing. Tobacco Specific N-nitrosamines (TSNAs) in tobacco leaves gradually increase during storage. The purpose of this study was to investigate the influence of sodium carbonate on the...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 33

    Quantitative risk assessment (QRA) indicates reduced risk potential for carcinogenic and non-carcinogenic effects of the aerosol of the next generation products (NGPs) compared to reference cigarettes

    AYALA-FIERRO F.(1); CZEKALA L.(2); SIMMS L.(2); RUDD K.(2); CAVA G.(2); STEVENSON M.(2)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) Imperial Brands PLC, Bristol, U.K.
    In order to understand the potential relative health risks of NGPs compared to cigarettes, we compared the relative risks of aerosols from tobacco-containing and tobacco-free NGPs to the smoke generated from a reference cigarette. Quantitative Risk...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 58

    A consortium approach for consumer-reported outcome measures to assess tobacco- and nicotine-containing products

    ACQUADRO C.(1) on behalf of the CORESTA CROM Task Force: AYALA-FIERRO F.(2); BLACK R.(3); CAHOURS X.(4); CHREA C.(5); CURTIN G.(6); GILES L.(7); McCAFFREY S.(3); PARK C.H.(8); PRASAD K.(9); SHERWOOD N.(10); SHIFFMAN S.(11); SMITH J.(6); SPIES E.(5)
    (1) Mapi Research Trust, Lyon, France; (2) ITG Brands, Greensboro, NC, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) SEITA - Imperial Brands, Paris, France; (5) Philip Morris Products S.A., Neûchatel, Switzerland; (6) RAIS, Winston-Salem, NC, U.S.A.; (7) JT Int'l SA, Genève, Switzerland; (8) KT&G Research Institute, Daejeon, Republic of Korea; (9) British American Tobacco, Southampton, U.K.; (10) Neil Sherwood Consulting, Commugny, Switzerland; (11) Pinney Associates, Pittsburgh, PA, U.S.A.
    In the tobacco space, consumer-reported outcome measures (CROM) are essential for understanding motivations, subjective effects, and behavior. Such measures have become particularly important with the advent of candidate modified risk tobacco...