Search Results

108 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 17

    Variation of soil potassium quantity-intensity relationship in flue-cured tobacco-rape rotation system under long-term located potassium application

    DAI Kuai(1); LI Jiangzhou(1); ZHANG Limeng(1); JI Sigui(1); LONG Huaiyu(2); XU Zhaoli(3); DUAN Yuqi(3); YANG Yuhong(3); LU Xiuping(3); JIAO Yongge(1); BU Lingduo(1)
    (1) Yunnan Tobacco Company Yuxi Branch/Biological Control of Tobacco Diseases and Insect Pests Engineering Research Center of China, Yuxi, P.R. China; (2) Institute of Agriculture Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, P.R. China; (3) Yunnan Tobacco Agriculture Research Institute, Kunming 650031, P.R. China
    The aim of this study was to explore the effect of long-term potassium application on soil potassium supply capacity, so as to provide certain scientific basis for rationalising potassium application and continuing research on the development of...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 12

    Determination of nicotine in gas vapour phase in phosphate buffered saline by UHPLC-MS/MS

    HOLLINGS M.(1); THOMPSON N.(2); LARNER J.(1); CLEMENTS J.(1)
    (1) Covance Laboratories Ltd, Harrogate, North Yorkshire, U.K.; (2) Broughton Nicotine Services, Earby, Lancashire, U.K.
    A liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method was developed to quantify nicotine in gas vapour phase (GVP) collected in calcium and magnesium free phosphate buffered saline (CMF-PBS). In this method the aerosol was trapped in...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 42

    Characterization of whole mainstream smoke/aerosol delivery within the Vitrocell® Ames 48 high throughput exposure module using different tobacco product types

    LEVERETTE R.(1); KEYSER B.(1); SEYMOUR A.(2); HOLLINGS M.(2)
    (1) RAI Services Company, Scientific & Regulatory Affairs, Winston-Salem, NC, U.S.A.; (2) Covance Laboratories Ltd, Otley Road, Harrogate, North Yorkshire, U.K.
    The preferred means of assessing combustible or other aerosol-generating tobacco products in vitro is by direct exposure of cell cultures to freshly generated whole mainstream smoke/aerosols. This approach eliminates the fractionation of...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 43

    Dosimetric analysis of aerosol generated by a Vitrocell® VC10® Smoking Robot – investigations on dose dependency and consistency of application

    SEYMOUR A.; HOLLINGS M.; LARNER J.; CLEMENTS J.
    Covance Laboratories Ltd, Harrogate, North Yorkshire, U.K.
    Quartz Crystal Microbalances were used to assess the suitability of the Vitrocell® VC10® exposure system. The main objective of the study was to deliver smoke aerosol in a consistent and dose dependent manner across a range of module formats. Dose...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 49

    The CORESTA in vitro test battery for combustible tobacco products: update from the 2004 Rationale and Strategy Report

    LEE K.M.(1); JORDAN K.G.(2); WIECZOREK R.(3); MOENNIKES O.(4); CLEMENTS J.(5); CROOKS I.(6); HASHIZUME T.(7); MILLER J.(8); WEBER E.(9); YOSHINO K.(7)
    (1) Altria Client Services, Richmond, VA, U.S.A.; (2) RAI Services Company, Winston-Salem, NC, U.S.A.; (3) Imperial Brands, Reemtsma Cigarettenfabriken GmbH, Hamburg, Germany; (4) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (5) Covance Laboratories Ltd, Harrogate, U.K.; (6) British American Tobacco (Investments) Ltd, R&D, Southampton, U.K.; (7) Japan Tobacco Inc., Yokohama, Kanagawa, Japan; (8) JT International SA, Geneva, Switzerland; (9) Ökolab, Vienna, Austria
    In 2004, the CORESTA In Vitro Toxicity Task Force issued a rationale and strategy report, commonly known as “the CORESTA in vitro test battery guideline”. The goals of this guideline were to: 1) develop the rationale and strategy for conducting in...
  6. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 049

    High throughput air liquid interface exposure modules: characterization of smoke/aerosol dosimetry and in vitro mutagenicity and cytotoxicity of two tobacco product types

    LEVERETTE R.(1); KEYSER B.(1); HOLLINGS M.(2); SEYMOUR A.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Covance Laboratories, North Yorkshire, UK
    The utilization of whole smoke/aerosol exposure systems provides a means to conduct in vitro assessments of freshly generated whole smoke/aerosol from combustible cigarettes and tobacco heating products (THPs), as well as electronic nicotine delivery...
  7. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 11

    Field trials with low nicotine tobacco varieties developed by conventional breeding technique: first results

    MALPICA A.(1); EVANS W.(2); ARCHIBALD C.(3); SCOTT L.(4); GARWE D.(5); CHAMANGO A.M.Z.(6); DORLHAC de BORNE F.(7); COLARD S.(8)
    (1) Bergerac Seed and Breeding, Bergerac, France; (2) Imperial Tobacco South Africa Pvt. Ltd, Umhlanga, Durban, South Africa; (3) Alliance One International Services, Camberley, Surrey, U.K.; (4) Universal Leaf Tobacco Co., Richmond, VA, U.S.A.; (5) Tobacco Research Board (TRB), Harare, Zimbabwe; (6) Agricultural Research & Extension Trust (ARET), Lilongwe, Malawi; (7) Imperial Tobacco Limited, Bergerac, France; (8) SEITA - Imperial Brands plc, Paris, France
    In 2015, the World Health Organisation (WHO) Study Group on Tobacco Product Regulation (“TobReg”) issued an advisory note recommending a strategy of reducing nicotine in tobacco to substantially lower levels of 0.4 mg/g. In the U.S., the Food and...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 25

    Misperception of e-cigarette harm growing among American adults, 2013-2015

    VERRON T.(1); GUO M.(1); VARIGNON B.(1); O'CONNELL G.(2); WALELE T.(2); CAHOURS X.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Fontem Ventures B.V., Amsterdam, The Netherlands
    Electronic cigarettes (e cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. However, the proportion of American adults who perceive e cigarettes to be equally or...
  9. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 12 (also presented at TSRC 2018)

    Characterization of the Vitrocell® high throughput exposure modules using different tobacco product types

    LEVERETTE R.(1); KEYSER B.(2); SEYMOUR A.(2); HOLLINGS M.(2); BOMBICK B.(1)
    (1) RAI Services Company, Scientific & Regulatory Affairs, Winston-Salem, NC, U.S.A.; (2) Covance Laboratories Ltd, Harrogate, North Yorkshire, U.K.
    The development of whole smoke/aerosol exposure systems provides a means to conduct in vitro assessment of freshly generated whole smoke and aerosol from combustible and tobacco heating products (THP) as well as electronic nicotine delivery systems...