1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 15

    Crystal structure of nicotine gentisate and its permeability in pig buccal mucosa

    YANG Ji; MIAO Mingming; CHEN Yongkuan; LIU Zhihua; ZHAO Yang; WU Yiqin; LIU Chunbo; YANG Liu; ZHAO Hui; SHEN Qinpeng; DUAN Yuanxing; GONG Xiaowei
    R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    Nicotine compound salt has been widely concerned recently with the continuous expansion of the e-cigarette market. Synthetic nicotine organic acid salt or nicotine complex, instead of monomeric nicotine, is used in the formulation of the next...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 27

    Determination of petroleum ether extracts in flue-cured tobacco leaves by NIR combined with random frog wavelength selection method

    QIU Changgui(1,2); LIU Ze(3); CHEN Shi(4); LIU Jing(1,2); WANG Jiajun(3); ZHANG Wen(1,2); YANG Panpan(1,2)
    (1) Yunnan Reascend Tobacco Technology (Group) Co., Ltd., Kunming, P.R. China; (2) Yunnan Comtestor Company, Kunming, P.R. China; (3) Technology Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China; (4) Bijie Cigarette Factory, China Tobacco Guizhou Industrial Co., Ltd., Bijie, P.R. China
    In order to improve the prediction accuracy and model stability for quantitative calibration in near infrared spectroscopy, the random frog wavelength selection method combined with partial least squares (PLS) was employed to establish the prediction...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 42

    Study on aerosol deposition in the respiratory tract of consumers using cigarette, electronic cigarette or heat-not-burn product

    CUI Huapeng(1); LI Yawen(1); FAN Meijuan(1); CHEN Li(1); SI Xiaoxi(2); HAN Jingmei(2); CAI Junlan(1); LI Xiang(1); LIU Shaofeng(1); XIE Fuwei(1); XIE Jianping(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China; (2) R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    The deposition of aerosols inhaled into the human respiratory tract is key to evaluate exposure and risk during product use. A method based on a differential mobility spectrometer (DMS) was established for determining the physical properties of...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 33

    Quantitative risk assessment (QRA) indicates reduced risk potential for carcinogenic and non-carcinogenic effects of the aerosol of the next generation products (NGPs) compared to reference cigarettes

    AYALA-FIERRO F.(1); CZEKALA L.(2); SIMMS L.(2); RUDD K.(2); CAVA G.(2); STEVENSON M.(2)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) Imperial Brands PLC, Bristol, U.K.
    In order to understand the potential relative health risks of NGPs compared to cigarettes, we compared the relative risks of aerosols from tobacco-containing and tobacco-free NGPs to the smoke generated from a reference cigarette. Quantitative Risk...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 58

    A consortium approach for consumer-reported outcome measures to assess tobacco- and nicotine-containing products

    ACQUADRO C.(1) on behalf of the CORESTA CROM Task Force: AYALA-FIERRO F.(2); BLACK R.(3); CAHOURS X.(4); CHREA C.(5); CURTIN G.(6); GILES L.(7); McCAFFREY S.(3); PARK C.H.(8); PRASAD K.(9); SHERWOOD N.(10); SHIFFMAN S.(11); SMITH J.(6); SPIES E.(5)
    (1) Mapi Research Trust, Lyon, France; (2) ITG Brands, Greensboro, NC, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) SEITA - Imperial Brands, Paris, France; (5) Philip Morris Products S.A., Neûchatel, Switzerland; (6) RAIS, Winston-Salem, NC, U.S.A.; (7) JT Int'l SA, Genève, Switzerland; (8) KT&G Research Institute, Daejeon, Republic of Korea; (9) British American Tobacco, Southampton, U.K.; (10) Neil Sherwood Consulting, Commugny, Switzerland; (11) Pinney Associates, Pittsburgh, PA, U.S.A.
    In the tobacco space, consumer-reported outcome measures (CROM) are essential for understanding motivations, subjective effects, and behavior. Such measures have become particularly important with the advent of candidate modified risk tobacco...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 64

    Analysis of cylinder drying intensity on cut strips based on Enthalpy method

    LIU Ze(1); LU Duanfeng(2); LI Bin(2); ZHU Yong(1); TANG Jun(1); ZHOU Bing(1); FU Liang(1); YANG Qianxu(1); HE Banghua(1)
    (1) R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China; (2) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China
    Cylinder drying of cut strips is one of the key technologies during the cigarette manufacturing process, which involves complex mass transfer and heat transfer phenomena. In order to study the actual cut strip heating and heat distribution in the...