1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 32

    Characterization and in vitro testing of whole smoke condensates from combustible cigarettes

    DOSHI U.(1); GARDNER W.P.(1); GILLMAN I.G.(2); LEE K.M.(1)
    (1) Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.; (2) Enthalpy Analytical, Inc., Richmond, VA, U.S.A.
    Health Canada recommends in vitro testing of separately collected gas and particulate phases of cigarette smoke for cytotoxicity and genotoxicity assessment. While these test materials have shown cytotoxicity and genotoxicity in literature, there has...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 34

    Characterization of an air-liquid-interface (ALI) in vitro exposure system (VITROCELL® VC1/7 and Ames 48) using a prototype e-vapor product

    ZHANG Jingjie(1); DOSHI U.(1); OLDHAM M.J.(1); COFFA B.G.(1); GILLMAN I.G.(2); WOLZ R.L.(2); KOSACHEVSHY P.(2); LEE K.M.(1)
    (1) Altria Client Services LLC, Richmond, VA, U.S.A.; (2) Enthalpy Analytical, Inc., Richmond, VA, U.S.A.
    Direct delivery of aerosol or vapor to the apical surface of cells (ALI) allows more relevant exposure for in vitro toxicological evaluation of inhalable chemicals. In this study, we quantitatively characterized the aerosol delivery in a commercially...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 63 (also presented at TSRC 2018)

    Challenges and opportunities in cigar science

    SMITH J.H.(1); AUBUCHON S.M.(1); WAGNER K.A.(1); McKINNEY W.J.(1); GILLMAN I.G.(2); STEVENS R.(3)
    (1) Altria Client Services LLC, Richmond, VA, U.S.A.; (2) Enthalpy Analytical, Inc., Henrico, VA, U.S.A.; (3) ITG Brands LLC, Greensboro, NC, U.S.A.
    An independent Cigar Working Group has been formed by interested cigar stakeholders (e.g. manufacturers and testing laboratories). The goals of the Working Group are to explore opportunities for engagement with the Food and Drug Administration (FDA)...
  4. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 054 (also presented at CORESTA 2018)

    Challenges and opportunities in cigar science

    SMITH J.H.(1); AUBUCHON S.M.(1); WAGNER K.A.(1); McKINNEY W.J.(1); GILLMAN I.G.(2); STEVENS R.(3)
    (1) Altria Client Services LLC, Richmond, VA, USA; (2) Enthalpy Analytical, Henrico, VA, USA; (3) ITG Brands LLC, Greensboro, NC, USA
    An independent Cigar Working Group was formed by interested cigar stakeholders (e.g. manufacturers and testing laboratories). The goals of the Working Group are to explore opportunities for engagement with the Food and Drug Administration (“FDA”) on...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 099a & 99b

    Machine made cigar leaf and product workshop

    STEVENS R.(1); BLACK R.(1); GILLMAN I.G.(2); SMITH J.(3); HARTLEY M.(4); LINDEGAARD T.(5)
    (1) ITG Brands LLC, Greensboro, NC, USA; (2) Enthalpy Labs, Durham, NC, USA; (3) Altria Client Services LLC, Richmond, VA, USA; (4) Universal Dark Air-Cured Group, Oxford, NC, USA
    The regulation of tobacco products continues to be a growing focus around the world. For example, in 2016, the FDA finalized a rule in the USA that extended its regulatory authority to all tobacco products, including e-cigarettes, cigars, hookah, and...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, ST 19

    Are chemical constituents exhaled in a room where e-vapor products are used?

    LIU J.(1); LIANG Q.(1); PENG X.(1); OLDHAM M.(1); ROSTAMI A.(1); WAGNER K.A.(1); GILLMAN I.G.(2); SALAPATEK A.M.(3); SARKAR M.(1)
    (1) Altria Client Services Inc., Richmond, VA, U.S.A.; (2) Enthalpy Analytical Inc., Durham, NC, U.S.A.; (3) Inflamax Research Inc., Toronto, Canada
    A controlled clinical study was conducted to determine potential constituents in the atmosphere where e-vapor products and cigarettes were used. Levels of nicotine, propylene glycol (PG), glycerol, 15 carbonyl compounds (including formaldehyde and...
  7. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 37

    Are chemical constituents exhaled in a room where e-vapor products are used?

    SARKAR M.(1); LIU J.(1); LIANG Q.(1); PENG X.(1); OLDHAM M.(1); ROSTAMI A.A.(1); WAGNER K.A.(1); GILLMAN I.G.(2); SALAPATEK A.M.(3)
    (1) Altria Client Services Inc., Richmond, VA USA; (2) Enthalpy Analytical Inc., Durham, NC USA; (3) Inflamax Research Inc., Toronto, Canada
    A controlled clinical study was conducted to determine potential constituents in the atmosphere where e-vapor products and cigarettes were used. Levels of nicotine, propylene glycol (PG), glycerol, 15 carbonyl compounds (including formaldehyde), 12...