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  1. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 11

    An inter-laboratory comparison of urinary 3-hydroxypropylmercapturic acid measurement demonstrates good reproducibility between laboratories.

    CHEUNG F.(1); MINET E.(1); ERRINGTON G.(1); MCEWAN M.(1); SCHERER G.(2); NEWLAND K.(3); SHARIFI M.(4); BAILEY B.(5)
    (1) British American Tobacco, Group R&D, Southampton, UK; (2) ABF GmbH; (3) Celerion; (4) Labstat International Inc.; (5). Covance Laboratories Ltd.
    Background- Biomarkers have been used extensively in clinical studies to assess toxicant exposure in smokers and non-smokers and have recently been used in the evaluation of novel tobacco products. The urinary metabolite 3-HPMA, a metabolite of the major ...
  2. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 40

    An evaluation of cema, and adducts of cysteinylglycine as potential biomarkers of exposure to acrylonitrile, formaldehyde, and acetaldehyde from cigarette smoke.

    MINET E.(1); CHEUNG F.(1); ERRINGTON G.(1); STERZ K.(2); SCHERER G.(2)
    (1) British American Tobacco, Group R&D, Southampton, UK; (2) Analytisch-Biologisches Forschungslabor GmbH, Munich, Germany
    Introduction: The WHO Study Group on Tobacco Product Regulation recommended a list of toxicants in mainstream smoke of cigarettes for mandated and recommended lowering. This list comprises 18 tobacco smoke constituents, including acrylonitrile, ...