Bull. Spec. CORESTA Symposium, Winston-Salem, 1982, p. 15, S05, ISSN.0525-6240
Racemization of nicotine and preparation of d-nicotine
Central Research Institute, Japan Tobacco & Salt Public Corp. Yokohama, Japan
To obtain dl-nicotine as starting material for preparation of d-nicotine, racemization of nicotine catalyzed by various bases was examined. As bases, NaOH, MeONa, EtONa, t-BuOK, NaH, NaNH2, CH3SOCH2Na, and LiNEt2 were used. It was found that the rate...