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86 results

  1. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 057

    CTP submissions – tips and insight for preparing an electronic submission

    SMITH J.K.(1); SHOLTES D.(1); GLATSTEIN S.(1); ANGERMEIER G.(2)
    (1) US Food and Drug Administration (FDA), Silver Spring, MD, USA; (2) WiseDesign, McLean, VA, USA
    Currently, tobacco product submissions are organized differently across application types and often, across applicants, and are received in a format that is not amenable for reviewers to organize and easily find what they need. This “unstructured”...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 079

    Comparison of the acetaldehyde, formaldehyde, and acrolein yields in cigars under different smoking regimens using a linear cigarette smoking machine

    YOUNG M.; CECIL T.L.; JOHNSON T.; FENG S.
    US Food and Drug Administration (FDA), Calverton, MD, USA
    Currently, there is very little information on the mainstream smoke yields of carbonyl compounds (e.g., formaldehyde, acetaldehyde, and acrolein) in cigar tobacco products. This study used a standard linear smoking machine and puffing protocols to...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 091

    Tobacco-specific nitrosamines in the mainstream smoke of commercial little cigars

    EDWARDS S.H.(1); HASSINK M.(1); TAYLOR K.M.(1); WATSON C.(2); KUKLENYIK P.(2); WANG R.(2); CHEN P.(2); VALENTIN-BLASINI L.(2); KIMBRELL B.(2)
    (1) US Food and Drug Administration (FDA), Silver Spring, MD, USA; (2) Centers for Disease Control and Prevention, Atlanta, GA, USA
    Cigars are among the broad variety of deemed tobacco products that have been less extensively studied and characterized than cigarettes. Small sheet-wrapped cigars, often called little cigars, are a subcategory of cigars that are similar to...
  4. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 048

    Survey of nicotine, NNK, NNN, pH and physical properties of little cigars in the US market place

    LIU Youbang(1); HASSINK M.D.(1); TAYLOR K.M.(1); WATSON C.(2); CHAFIN D.(2); LAWLER T.(2); VALENTIN-BLASINI L.(2); KIMBRALL B.(2)
    (1) U.S. Food and Drug Administration, Silver Spring, MD, USA; (2) Centers for Disease Control and Prevention, Atlanta, GA, USA
    In May 2016, the jurisdiction of the Federal Food Drug and Cosmetic Act was extended to include all tobacco products, including cigars. Because limited information exists on the chemistry of cigar filler and smoke, 60 brands of popular little cigars...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 098

    CTP submissions – tips and insight for preparing an electronic submission

    SHOLTES D.(1); SMITH J.K.(1); ANGERMEIER G.(2)
    (1) U.S. Food & Drug Administration, Silver Spring, MD, USA; (2) WiseDesign, McLean, VA, USA
    Currently, tobacco product submissions are organized differently across application types and often, across applicants, and are received in a format that is not amenable for reviewers to organize and easily find what they need. This “unstructured”...
  6. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 078

    Development of a multi-stage liquid extraction method for the quantitative analysis of flavors in tobacco filler

    MATHIS J.A.; STANELLE R.A.; DIMANDIA J.-M.D.
    U.S. Food and Drug Administration, Atlanta, GA, USA
    A method to quantify flavor chemicals in the filler of combustible tobacco products was validated using GC-MS. The tobacco filler samples from cigarettes, little cigars, cigarillos, and cigars were prepared in a multi-step extraction procedure using...
  7. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, AP 54

    The regulation of autophagy of susceptible Nicotiana tabacum under tobacco mosaic virus infection

    YANG Jinguang(1); LIU Xaingfu(1); LIU Wei(1); QIAN Yumei(1); ZHANG Jing(2); LI Wei(2); DONG Shifei(2); WANG Yaofeng(3); HUANG Mingdi(4); WANG Fenglong(1)
    (1) Tobacco Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Tobacco Pest Monitoring Controlling & Integrated Management, Qingdao, P.R. China; (2) Hongyun Honghe Tobacco (Group) Co., Ltd., Kunming, P.R. China; (3) Qingyang Branch of Gansu Province Tobacco Company, Xifeng, P.R. China; (4) Longnan Tobacco Company, Gansu Tobacco Cooperation, Wudu 746000, P.R. China
    Autophagy (or self-eating) is an important conserved process by which eukaryotic cells recycle intracellular components. This study was undertaken to elucidate whether tobacco mosaic virus (TMV) infection on tobacco plants induced autophagy. TMV-U1...