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111 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 40

    Progress in breeding and biocontrol dual approaches for tobacco broomrape management

    MALPICA A.(1); GUINCHARD L.(2); BACHET S.(1); VACHER C.(3); GATARD L.(4); REIBEL C.(2); GAUTHERON N.(2); EDELHERMANN V.(2); STEINBERG C.(2); GIBOT LECLERC S.(2)
    (1) Bergerac Seed & Breeding, Bergerac, France; (2) Agroécologie (AgroSup Dijon, INRA, Univ. Bourgogne Franche-Comté), Dijon, France; (3) Arvalis, Institut du Vegetal, Bergerac, France; (4) Coopérative CT2F, Maison de l’Agriculture, Schiltigheim, France
    Tobacco broomrape (Phelipanche ramosa, Phelipanche aegyptiaca and Orobanche Cernua) is a widespread parasitic plant from the Orobanchaceae family, that causes important damage in tobacco crops. Broomrape is mainly present in Europe, Middle East and...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 27

    Next generation product aerosol bubbled extracts show little to no effect in high content screening endpoints when compared to cigarette smoke bubbled extracts

    TRELLES STICKEN E.(1); WIECZOREK R.(1); BODE L.M.(1); SIMMS L.(2); STEVENSON M.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), BioToxLab, Hamburg, Germany; (2) Imperial Tobacco Limited, In vitro Research, Bristol, U.K.
    Tobacco-based and tobacco-free next generation products (NGPs) are understood to be a less harmful alternative to conventional combustible cigarettes. The objective of this study was to compare the in vitro biological response of cigarette smoke...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 34

    Next generation product aerosols induce lower biological activity than combusted cigarettes: a comparison of in vitro cell migration in the scratch wound assay

    RUDD K.(1); BUDDE J.(2); TRELLES STICKEN E.(2); WIECZOREK R.(2); SIMMS L.(1); STEVENSON M.(1)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    Smoking combustible cigarettes is a cause of serious diseases in smokers, including heart disease. There are many commercially available next generation products (NGPs), such as tobacco-free e-vapour products, aiming to provide an alternative to...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 37

    Use of cell media nicotine concentration as a marker to predict cells surface deposited nicotine in transwells after fresh smoke/aerosol exposure

    WIECZOREK R.(1); TRELLES STICKEN E.(1); BODE L.M.(1); SIMMS l.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Imperial Tobacco Limited, Bristol, U.K.
    Exposure of organotypic 3D lung models at the air liquid interface (ALI) to fresh whole smoke/aerosol provides a more human relevant exposure assessment of combustible cigarettes and e-vapour products. The aim of this study is to present a method...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STW 01

    The application of in vitro Toxicity Testing in 21 Century (TT21C) for next generation products

    SIMMS L.(1); TRELLES STICKEN E.(2)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The aim is to demonstrate the feasibility of TT21C in vitro methods as part of an overall assessment framework for next generation products (NGP). TT21C methodologies can be used to assess harm reduction potential of NGPs using human-derived...
  6. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 14

    RNA-Seq analysis of Orobanche resistance in tobacco: development of molecular markers for breeding recessive resistance from Wika tobacco variety

    JULIO E.(1); MALPICA A.(2); COTUCHEAU J.(1); BACHET S.(2); VOLPATTI R.(1); DECORPS C.(1); DORLHAC de BORNE F.(1)
    (1) Imperial Tobacco Limited, Leaf Research, Bergerac, France; (2) Bergerac Seed and Breeding, Bergerac, France
    Orobanche spp. (broomrape) is an obligate root parasite that can attack a wide spectrum of plants, including tobacco. It is responsible for economic losses in Europe since 2002 and its incidence in many tobacco growing countries is increasing....
  7. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 11

    Field trials with low nicotine tobacco varieties developed by conventional breeding technique: first results

    MALPICA A.(1); EVANS W.(2); ARCHIBALD C.(3); SCOTT L.(4); GARWE D.(5); CHAMANGO A.M.Z.(6); DORLHAC de BORNE F.(7); COLARD S.(8)
    (1) Bergerac Seed and Breeding, Bergerac, France; (2) Imperial Tobacco South Africa Pvt. Ltd, Umhlanga, Durban, South Africa; (3) Alliance One International Services, Camberley, Surrey, U.K.; (4) Universal Leaf Tobacco Co., Richmond, VA, U.S.A.; (5) Tobacco Research Board (TRB), Harare, Zimbabwe; (6) Agricultural Research & Extension Trust (ARET), Lilongwe, Malawi; (7) Imperial Tobacco Limited, Bergerac, France; (8) SEITA - Imperial Brands plc, Paris, France
    In 2015, the World Health Organisation (WHO) Study Group on Tobacco Product Regulation (“TobReg”) issued an advisory note recommending a strategy of reducing nicotine in tobacco to substantially lower levels of 0.4 mg/g. In the U.S., the Food and...
  8. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 42

    Progress in development of a high-throughput phenotyping test as breeding tool for broomrape resistance in tobacco: an overview of results

    MALPICA A.(1); VERRIER J.-L.(1); BACHET S.(1); BEN JEMAA F.(2); POUVRAUD J.-B.(2); SIMIER P.
    (1) Bergerac Seed & Breeding, Bergerac, France; (2) Laboratoire de Biologie et de Pathologie Végétale, Nantes University, Nantes, France
    Tobacco broomrape (Phelipanche ramosa) is a widespread parasitic plant that causes serious damage in some countries. Selection of resistant varieties is an essential pillar of an integrated broomrape control strategy but research performed on...