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121 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 23

    A statistical analysis of variability in polyaromatic hydrocarbons (PAHs) from reference and commercial cigarettes

    WAGSTAFF W.; RICKERT W.; JOZA P.
    Labstat international ULC, Kitchener, Ontario, Canada
    This study was conducted to characterize the variability of mainstream PAH emissions data and to investigate the ability to detect differences amongst products. The mainstream yields of a reference cigarette (Kentucky Reference 3R4F) were obtained for a ...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 049

    Assessment of in vitro toxicity/genotoxicity of ends and combustible products

    JORDAN K.(1); BOMBICK B.(1); COOPER B.(1); LEVERETTE R.(1); SHUTSKY T.(1); WEST C.(1); STRASSER J.(1); ROUND E.(1); MARANO K.M.(1); MOMIN R.(2); TRIVEDI A.(2); WAGSTAFF W.(2); BRUCE S.(3); DAKOULAS E.(3); ROY S.(3)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Labstat International ULC, Kitchener, ON, Canada; (3) BioReliance Corp, Rockville, MD, USA
    In May 2016, the U.S. Food and Drug Administration Center for Tobacco Products (CTP) issued draft guidance for Premarket Tobacco Product Applications (PMTA) for Electronic Nicotine Delivery Systems (ENDS), which recommends inclusion of in vitro toxicology ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 19

    An alternative strategy for the determination of pH values of aerosol from electronic cigarettes

    JOZA P.; MOHAMMAD A.; RICKERT W.S.
    Labstat International ULC, Kitchener, ON, Canada
    Any pH determination to measure the effective acid-base properties of an aerosol is dependent on the measurement technique. Determinations of aerosol pH using puff-by-puff collections are influenced by the buffer used to condition the electrode, while ...
  4. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 047

    The impact of 2, 4-dinitrophenylhydrazine (DNPH) background in the determination of carbonyls compounds in e-cigarette vapor

    DONISA C.; JOZA P.; RODRIGUEZ-LAFUENTE A.; RICKERT W.S.
    Labstat International, Kitchener, ON, Canada
    Carbonyl compounds, are known to be present in some e-liquid formulations and can be formed during aerosol generation. Analysis of these compounds, as their hydrazones (2,4-dinitrophenylhydrazine; DNPH) are routinely performed using high performance ...
  5. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 087

    Analysis of organic acid content in e-liquids and e-cigarette aerosol by high performance liquid chromatography – ultraviolet detection (HPLC-UV)

    RODRIGUEZ-LAFUENTE A.; LODEVICO R.; SHARIFI M.; JOZA P.; RICKERT W.S.
    Labstat International, Kitchener, ON, Canada
    Weak organic acids can be used as preservative agents, potentially affecting the stability of e-cigarette solutions. However, they can also impact characteristics like the aroma and taste of aerosols. The objective of this study was to develop and ...
  6. 47th TWC, Tob. Work. Conf., 2016, abstr. 29

    Working towards an increased understanding of the genetics of soil-borne disease resistance in tobacco

    DRAKE K.(1); LEWIS R.S.(1); BAKAHER N.(2); GOEPFERT S.(2); PHILIPPON B.(2); MARK R.(2); PETERSON P.D.(3)
    (1) North Carolina State University, Raleigh NC USA; (2) Philip Morris International, Neuchatel, Switzerland; (3) Clemson University, Florence SC USA
    Black shank and bacterial wilt, caused by Phytophthora nicotianae and Ralstonia solanacearum, respectively, are the most important diseases affecting tobacco production in the United States. An increased understanding of the genetic systems controlling ...