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2 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2011, Graz, ST 32

    Comparison of cigarette smoke cytotoxicities using different assay systems, Neutral Red uptake assay and WST-1 assay

    TANAKA H.; NISHIO Y.; FUKUSHIMA T.
    Product Science Division, Japan Tobacco Inc., Yokohama, Kanagawa, Japan
    Cytotoxic assays are used as part of a test battery to assess potential risk of cigarette smoke. So far, cytotoxic assays have been established indicative of various measurement endpoints, such as cell proliferation inhibition, enzymatic inhibition and ...
  2. TSRC, Tob. Sci. Res. Conf., 2009, 63, abstr. 62

    Effect of temperature and atmosphere on the mutagenicity and cytotoxicity of smoke condensate in tobacco pyrolysis

    OTSU Y.; NISHIO Y.; YOSHIDA S.
    Japan Tobacco Inc., Research Center, Yokohama, Kanagawa, Japan
    Total particulate matter (TPM) generated by the combustion of tobacco leaves shows in vitro biological activities. Tobacco leaves are subjected to a wide range of temperatures and oxygen concentrations during cigarette smoking. It is known that the ...