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3 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 37

    Good relationship between saliva cotinine kinetics and plasma cotinine kinetics after smoking one cigarette

    YUKI D.; KIKUCHI A.; MIURA N.; KAKEHI A.; ONOZAWA M.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    This study investigated the relationship between plasma and saliva cotinine kinetics after smoking one cigarette and the relationship between cotinine kinetics and estimated nicotine intake, which was calculated as mouth level exposure (MLE) of nicotine, ...
  2. CORESTA Congress, Paris, 2006, SS 31

    Differences in the generation of 8-hydroxyguanine by cigarette smoke in calf-thymus DNA and in A549 cells

    MIURA N.; FUKANO Y.; NISHINO T.
    Japan Tobacco Inc., Tobacco Science Research Lab., Yokohama, Kanagawa, Japan.
    In this report we investigated the generation of 8-hydroxyguanine by cigarette smoke using calf-thymus DNA and A549 cells. At first, we exposed the calf-thymus DNA to cigarette smoke bubbled PBS and measured the amount of 8-OhdG, which is the hydrolysate ...
  3. CORESTA Meeting, Smoke Science/Product Technology, Freiburg, 2003, ST 17

    A study of the degradation process of chlorogenic acid during pyrolysis

    NAKAMORI T.; MIURA N.; SUZUKI M.; SHIKATA H.
    Japan Tobacco Inc., Tobacco Science Research Lab., Yokohama, Kanagawa, Japan.
    Chlorogenic acid, which is one of the major polyphenols in tobacco leaves, is considered to be one of the major precursors for phenolic compounds in tobacco smoke. The purpose of this study is to reveal the degradation process of chlorogenic acid during ...