1. CORESTA Congress, Paris, 2006, SS 31

    Differences in the generation of 8-hydroxyguanine by cigarette smoke in calf-thymus DNA and in A549 cells

    MIURA N.; FUKANO Y.; NISHINO T.
    Japan Tobacco Inc., Tobacco Science Research Lab., Yokohama, Kanagawa, Japan.
    In this report we investigated the generation of 8-hydroxyguanine by cigarette smoke using calf-thymus DNA and A549 cells. At first, we exposed the calf-thymus DNA to cigarette smoke bubbled PBS and measured the amount of 8-OhdG, which is the hydrolysate ...