1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 32

    Enumeration of TBNK cells: A case for a bioanalytical assay to support clinical studies for the development of modified risk tobacco products

    NEWLAND K.; MILLER P.; FARMEN R.
    Celerion, Inc., Lincoln, NE, U.S.A.
    Smoking has been reported to lessen the body’s immune response making it more susceptible to infections. Chronic cigarette smoke exposure causes imbalance in immune homeostasis affecting the circulating immune cells. Peripheral blood lymphocytes are ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 17

    A clinical study investigating changes in exposure to cigarette smoke chemicals in U.K. smokers who switch to using a tobacco heating product for a five-day period

    McEWAN M.(1); EBAJEMITO J.K.(1); GALE N.(1); ELDRIDGE A.(1); CAMACHO O.M.(1); MURPHY J.(1); HARDIE G.(1); PROCTOR C.J.(1)
    (1) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.; (2) Celerion Inc., Lincoln, NE, U.S.A.
    Smoking is a leading cause of numerous diseases, particularly lung cancer, chronic obstructive pulmonary disease and cardiovascular diseases. Consequently, there is a recognized need to provide smokers with alternative nicotine-delivery devices that have ...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 39

    Impact of cigarette paper and blend on super slim, slim and king-size cigarette designs

    WANNA J.(1); CHEN Cai(2); XIAO Cuicui(3); LIANG Chenze(3); RUI Li(4); ZHANG Wenjun(4)
    (1) SWM Intl., Alpharetta, GA, U.S.A.; (2) SWM Shanghai Representative Office, Shanghai, P.R. China; (3) China Tobacco Mauduit, Jiangmen, Guangdong, P.R. China; (4) China Tobacco Schweitzer, Yuxi City, Yunnan, P.R. China
    Superslim (SS) cigarettes account for 5 % of total cigarette sales on the Chinese market, with a year to year increase of 2.1 %. Similar to this fast-growing trend, many more brands of slim (SL) cigarettes have been offered on the market since 2017. To ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 44

    Time and spatially resolved in-situ determination of temperature, pressure and gas phase concentration of selected smoke constituents inside a burning superslim cigarette. Part I – Thermophysical mapping

    CUI Huapeng(1); EHLERT S.(2); XIE Fuwei(1); DENG Nan(1); LI Bin(1); LIU Chuan(3); McADAM K.(3); WALTE A.(2); ZIMMERMANN R.(2)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco (Investments) Limited, Global R&D, Southampton, U.K.
    Superslim cigarettes in China are a relevant product category on the market. Accurate determination of key thermo-physical and-chemical parameters in superslim cigarettes are essential for the mechanistic understanding of combustion as well as pyrolysis ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 47

    Study on reducing the fragmentation rate of paper-making reconstituted tobacco during the cutting process in the cigarette factory

    ZHANG Wenjun(1); TENNIER J.(2); TU Yangang(1); ZHANG Yan(3); ZHENG Jianyu(1); ZHANG Mengyuan(1); LI Rui(1); LIU Jing(1); XIONG Zhen(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.; (3) Yunnan Tobacco Quality Supervision and Inspection Station, Kunming, Yunnan, P.R. China
    It is known that reconstituted tobacco leaf tends to generate dust and particles during the cutting process in the cigarette factory. To solve the issue, analysis of the composition structure of manufacturing waste was carried out. Effects on the ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 48

    Research on colour improvement of paper-making reconstituted tobacco

    SU Dandan(1); TU Yangang(1); ZHANG Wenjun(1); TENNIER J.(2); WEI Mingwen(1); WANG Xiaosheng(1); FENG Tao(1); MI Lan(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.
    Paper-making reconstituted tobacco (PRT) is an important raw material for the tobacco industry, with various benefits including reducing cost, smoke tar delivery, and impact on the environment. The different appearance of PRT compared to regular cigarette ...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 59

    An inter-laboratory comparison study focused on the determination of total NNAL in human urine

    NEWLAND K.(1); SCHERER M.(2); HECHT S.S.(3); TROUDE V.(4); PRASAD G.L.(5)
    (1) Celerion Inc., Lincoln, NE, U.S.A.; (2) ABF GmbH, Planegg, Germany; (3) University of Minnesota Cancer Center, Minneapolis, MN, U.S.A.; (4) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (5) RAI Services Company, Winston-Salem, NC, U.S.A.
    In an ongoing effort to fulfil the second objective of the CORESTA Biomarker Sub-Group, periodic inter-laboratory comparison studies have been performed to evaluate the consistency of the quantitation for various harmful or potentially harmful exposure ...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 47

    Effect of ethanol concentration on chemical composition of tobacco extracts

    ZHENG Jianyu(1); LIU Changbo(1); ZHANG Wenjun(1); TENNIER J.(2); FU Yin(1); XIONG Zhen(1); CHEN Shaoquan(1); FENG Tao(1); WANG Yanhong(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.
    Ethanol is widely used as a solvent in the chemical, pharmaceutical, and biological industries, for the extraction of various natural products, including those from tobacco. In this study, an ethanol-water system with four different concentrations of ...
  9. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 014

    Analysis of isotopically labeled glycerol to measure exposure from e-cigarettes

    DIBBERN E.M.; KAFONEK C.J.; BROWN G.P.; DZERK A.M.; NACHI R.; NEWLAND K.E.; ISLAM R. (presented by Erika Pfaumiller)
    Celerion, Lincoln, NE, USA
    Electronic cigarettes (ecigs) have become a popular mode of nicotine ingestion. They are often promoted as being less harmful than traditional cigarettes, but research supporting that claim is incomplete. The main chemical components of ecigs are ...